Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | TDO2 | P48775 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2556098 | 0.92 | IDO1 (0.42) | LMNAMAPTDHODHALDH1A1NPSR1 | |
| SCHEMBL2562174 | 0.91 | LMNA (0.38) | LMNAMAPTDHODHHTTALDH1A1 | |
| SCHEMBL2563057 | 0.88 | DHODH (0.38) | MAPTDHODHIDO1TDO2PTGS2 | |
| SCHEMBL15330731 | 0.87 | IDO1 (0.43) | LMNAMAPTHTTALDH1A1IDO1 | |
| SCHEMBL15332030 | 0.87 | S1PR1 (0.37) | LMNAMAPTDHODHHTTIDO1 | |
| SCHEMBL2561033 | 0.87 | MAPK14 (0.42) | LMNADHODHHTTALDH1A1POLB | |
| SCHEMBL29951687 | 0.87 | S1PR1 (0.37) | LMNAMAPTDHODHHTTIDO1 | |
| SCHEMBL2560291 | 0.87 | DHODH (0.37) | LMNAMAPTDHODHIDO1TDO2 | |
| SCHEMBL2563840 | 0.86 | LMNA (0.40) | LMNAMAPTHTTALDH1A1NPSR1 | |
| SCHEMBL29951228 | 0.86 | KCNN4 (0.42) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |