Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK7 | P50613 | 1/20 | 0.34 |
| ▸ | CCNH | P51946 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 3/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15332030 | 1.00 | S1PR1 (0.37) | S1PR1MAPK14LMNAPOLBDHODH | |
| SCHEMBL2559144 | 0.92 | LMNA (0.36) | S1PR1LMNADHODHSRCBRAF | |
| SCHEMBL2551849 | 0.91 | IDO1 (0.40) | POLBDHODHIDO1TDO2 | |
| SCHEMBL2561033 | 0.90 | MAPK14 (0.42) | MAPK14LMNAPOLBDHODHHTT | |
| SCHEMBL15333108 | 0.89 | TRPV1 (0.38) | POLBIDO1TDO2 | |
| SCHEMBL2562683 | 0.89 | LMNA (0.41) | LMNASRCBRAFKDRIDO1 | |
| SCHEMBL15332452 | 0.89 | DHODH (0.34) | DHODHIDO1TDO2 | |
| SCHEMBL15332960 | 0.88 | KMT2A (0.40) | MAPK14LMNAPOLBHTTFABP3 | |
| SCHEMBL2559756 | 0.88 | IDO1 (0.37) | LMNADHODHMAPTKIF11IDO1 | |
| SCHEMBL15329948 | 0.87 | LMNA (0.40) | LMNAPOLBDHODHMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |