Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.38 |
| ▸ | FPR2 | P25090 | 5/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | MAT2A | P31153 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2560383 | 0.96 | ALDH1A1 (0.41) | ARALDH1A1SMN1; SMN2SCN9AFPR2 | |
| SCHEMBL2556134 | 0.85 | ALDH1A1 (0.52) | ARALDH1A1SMN1; SMN2SCN9AFPR2 | |
| SCHEMBL2558638 | 0.83 | PDK2 (0.37) | ALDH1A1SMN1; SMN2MAPTPDK2 | |
| SCHEMBL2559256 | 0.82 | ALDH1A1 (0.55) | ARALDH1A1SMN1; SMN2SCN9AFPR2 | |
| SCHEMBL2556192 | 0.76 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2SCN9AFPR2OPRM1 | |
| SCHEMBL15331157 | 0.75 | AR (0.46) | ARALDH1A1SMN1; SMN2ELANEMAT2A | |
| SCHEMBL2559298 | 0.75 | ALDH1A3 (0.55) | ARALDH1A1SMN1; SMN2ELANEMAPT | |
| SCHEMBL2558605 | 0.74 | CYP3A4 (0.48) | ALDH1A1SMN1; SMN2MAPTMAOAPDK2 | |
| SCHEMBL29382076 | 0.74 | ELANE (0.42) | ARSCN9AFPR2ELANEMAPT | |
| SCHEMBL2559290 | 0.73 | AR (0.50) | ARALDH1A1SCN9AFPR2ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |