SCHEMBL15330301

SCHEMBL15330301

O=Cc1ccn(CCC(=O)O)c1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EGLN3 Q9H6Z9 1/20 0.41
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
LMNA P02545 1/20 0.37
FABP3 P05413 1/20 0.36
FABP4 P15090 1/20 0.36
FABP5 Q01469 1/20 0.36
ALDH1A1 P00352 4/20 0.35
PKM P14618 1/20 0.35
APEX1 P27695 1/20 0.35
MAPT P10636 1/20 0.35
AKR1B1 P15121 1/20 0.34
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ESR1 P03372 1/20 0.34
KMO O15229 1/20 0.33
FFAR1 O14842 1/20 0.33
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9192984 0.81 AKR1B1 (0.51) KMT2AALDH1A1MAPTAKR1B1KDM4E
SCHEMBL16984016 0.76 ALDH1A1 (0.35) MEN1KMT2ALMNAALDH1A1MAPT
SCHEMBL11908469 0.74 ALDH1A1 (0.46) EGLN3MEN1KMT2ALMNAFABP3
SCHEMBL11334483 0.73 NPC1 (0.42) LMNAALDH1A1MAPTMAPK1SMN1; SMN2
SCHEMBL6348803 0.71 TYR (0.55) EGLN3MEN1KMT2ALMNAFABP3
SCHEMBL11337869 0.71 NPC1 (0.49) MEN1KMT2ALMNAALDH1A1MAPT
SCHEMBL23541176 0.70 EGLN3 (0.43) EGLN3MEN1KMT2AALDH1A1MAPT
SCHEMBL22342727 0.70 NPC1 (0.50) MEN1KMT2ALMNAALDH1A1MAPT
SCHEMBL22342731 0.70 NPC1 (0.50) MEN1KMT2ALMNAALDH1A1MAPT
SCHEMBL22342726 0.70 NPC1 (0.50) MEN1KMT2ALMNAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119751188-A Screening preparation method and application of anti-inflammatory and antioxidant activity of ramulus et folium Broussonetiae extract 云南农业大学 2025-04-04 CN claimed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-11376334-B2 Hydrazinyl-substituted heteroaryl compounds and methods for producing a conjugate R.P. SCHERER TECHNOLOGIES, LLC (US) 2022-07-05 US disclosed
US-11376334-B2 Hydrazinyl-substituted heteroaryl compounds and methods for producing a conjugate R.P. SCHERER TECHNOLOGIES, LLC (US) 2022-07-05 US disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
US-20200405876-A1 Hydrazinyl-Substituted Heteroaryl Compounds and Methods for Producing a Conjugate ARES CAPITAL CORPORATION, AS COLLATERAL AGENT 2020-12-31 US disclosed
US-20200405876-A1 Hydrazinyl-Substituted Heteroaryl Compounds and Methods for Producing a Conjugate ARES CAPITAL CORPORATION, AS COLLATERAL AGENT 2020-12-31 US disclosed
US-10758628-B2 Hydrazinyl-substituted heteroaryl compounds and methods for producing a conjugate R.P. SCHERER TECHNOLOGIES, LLC (US) 2020-09-01 US disclosed
US-20190192680-A1 Hydrazinyl-Substituted Heteroaryl Compounds and Methods for Producing a Conjugate REDWOOD BIOSCIENCE, INC. 2019-06-27 US disclosed
US-10195283-B2 Hydrazinyl-substituted heteroaryl compounds and methods for producing a conjugate R.P. SCHERER TECHNOLOGIES, LLC (US) 2019-02-05 US disclosed
US-10195283-B2 Hydrazinyl-substituted heteroaryl compounds and methods for producing a conjugate R.P. SCHERER TECHNOLOGIES, LLC (US) 2019-02-05 US disclosed
EP-2558577-B1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION AS (DK) 2018-12-12 EP disclosed
US-20170266302-A1 Hydrazinyl-Substituted Heteroaryl Compounds and Methods for Producing a Conjugate R.P. SCHERER TECHNOLOGIES, LLC 2017-09-21 US disclosed
US-20170266302-A1 Hydrazinyl-Substituted Heteroaryl Compounds and Methods for Producing a Conjugate R.P. SCHERER TECHNOLOGIES, LLC 2017-09-21 US disclosed
US-20170266302-A1 Hydrazinyl-Substituted Heteroaryl Compounds and Methods for Producing a Conjugate R.P. SCHERER TECHNOLOGIES, LLC 2017-09-21 US disclosed
US-20130281324-A1 BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2013-10-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10195283-B2 Hydrazinyl-substituted heteroaryl compounds and methods for producing a conjugate HNMT, TIAL1, HACL2 EGLN3 1515/4885MEN1 491/4885KMT2A 515/4885
US-20190192680-A1 Hydrazinyl-Substituted Heteroaryl Compounds and Methods for Producing a Conjugate HNMT, TIAL1, HACL2 EGLN3 1515/4885MEN1 491/4885KMT2A 515/4885
US-20170266302-A1 Hydrazinyl-Substituted Heteroaryl Compounds and Methods for Producing a Conjugate HNMT, TIAL1, HACL2 EGLN3 1515/4885MEN1 491/4885KMT2A 515/4885
US-11376334-B2 Hydrazinyl-substituted heteroaryl compounds and methods for producing a conjugate HNMT, TIAL1, HACL2 EGLN3 1515/4885MEN1 491/4885KMT2A 515/4885
US-10758628-B2 Hydrazinyl-substituted heteroaryl compounds and methods for producing a conjugate HNMT, TIAL1, HACL2 EGLN3 1515/4885MEN1 491/4885KMT2A 515/4885
US-20200405876-A1 Hydrazinyl-Substituted Heteroaryl Compounds and Methods for Producing a Conjugate HNMT, TIAL1, HACL2 EGLN3 1515/4885MEN1 491/4885KMT2A 515/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.