SCHEMBL15330346

SCHEMBL15330346

CCOc1ccc2[nH]c(-c3ccc(CC)cc3)c(C=O)c2c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.46
HSD17B10 Q99714 3/20 0.46
ALDH1A1 P00352 3/20 0.46
MEN1 O00255 2/20 0.46
KDM4E B2RXH2 2/20 0.46
TSHR P16473 1/20 0.46
TUBB4A P04350 1/20 0.45
TUBB P07437 1/20 0.45
TUBA3C P0DPH7 1/20 0.45
TUBA1B P68363 1/20 0.45
TUBA4A P68366 1/20 0.45
TUBB4B P68371 1/20 0.45
TUBB3 Q13509 1/20 0.45
TUBB2A Q13885 1/20 0.45
TUBB8 Q3ZCM7 1/20 0.45
TUBA3E Q6PEY2 1/20 0.45
TUBA1A Q71U36 1/20 0.45
TUBA1C Q9BQE3 1/20 0.45
TUBB6 Q9BUF5 1/20 0.45
TUBB2B Q9BVA1 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15330982 0.89 KDM4E (0.50) KMT2AHSD17B10ALDH1A1MEN1KDM4E
SCHEMBL15331703 0.89 TUBB4A (0.54) KMT2AHSD17B10ALDH1A1MEN1KDM4E
SCHEMBL15329569 0.88 KDM4E (0.49) KMT2AHSD17B10ALDH1A1MEN1KDM4E
SCHEMBL15332104 0.88 MAPT (0.49) KMT2AHSD17B10ALDH1A1MEN1KDM4E
SCHEMBL15331100 0.82 PTGS2 (0.43) KMT2AHSD17B10ALDH1A1MEN1KDM4E
SCHEMBL2558994 0.81 PTGS2 (0.44) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL15331697 0.81 PTGS2 (0.47) HSD17B10ALDH1A1KDM4EHPGDAHR
SCHEMBL2558018 0.81 MEN1 (0.47) KMT2AHSD17B10ALDH1A1MEN1KDM4E
SCHEMBL15332742 0.81 MEN1 (0.46) KMT2AALDH1A1MEN1KDM4EMAPT
SCHEMBL15332543 0.80 KDM4E (0.46) KMT2AHSD17B10ALDH1A1MEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-11225655-B2 Bi-functional complexes and methods for making and using such complexes NUEVOLUTION A/S (DK) 2022-01-18 US disclosed
EP-3540059-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES Nuevolution A/S (DK) 2019-09-18 EP disclosed
EP-2558577-B1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION AS (DK) 2018-12-12 EP disclosed
US-20130281324-A1 BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2013-10-24 US disclosed
US-20120126690-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION 2012-05-24 US disclosed