Hydrochloric Acid

Hydrochloric Acid

SCHEMBL1533049

C=CC[n+]1ccccc1C=C.[Cl-]

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 3/20 0.36
HDAC8 Q9BY41 1/20 0.48
KDM4E B2RXH2 2/20 0.45
BCHE P06276 1/20 0.36
ALDH1A1 P00352 2/20 0.31
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
MAPT P10636 1/20 0.31
STAT3 P40763 1/20 0.31
HTT P42858 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL721593 0.98 HDAC8 (0.50) HDAC8KDM4EACHEBCHEALDH1A1
Iodide SCHEMBL4396612 0.96 HDAC8 (0.48) HDAC8KDM4EACHEBCHEALDH1A1
Water SCHEMBL9445052 0.96 HDAC8 (0.48) HDAC8KDM4EACHEBCHEALDH1A1
Hydrochloric Acid SCHEMBL1171580 0.80 HDAC8 (0.53) HDAC8KDM4EACHEBCHEALDH1A1
SCHEMBL11004432 0.79 KDM4E (0.43) HDAC8KDM4EACHEBCHENPC1
Bromide SCHEMBL7942908 0.78 HDAC8 (0.52) HDAC8KDM4EACHEBCHEALDH1A1
SCHEMBL7764476 0.78 NPC1 (0.47) HDAC8KDM4EACHEALDH1A1MEN1
SCHEMBL29444179 0.78 ACHE (0.51) HDAC8KDM4EACHEBCHENPC1
SCHEMBL153132 0.78 HDAC8 (0.55) HDAC8KDM4EACHEALDH1A1MEN1
SCHEMBL29838155 0.78 HDAC8 (0.55) HDAC8KDM4EACHEALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2204875-B1 Electrolyte composition and photoelectric conversion element using same FUJIKURA LTD (JP) 2011-09-28 EP disclosed
EP-2204876-B1 Electrolyte composition and photoelectric conversion element using same FUJIKURA LTD (JP) 2011-09-28 EP disclosed
EP-1655799-B1 ELECTROLYTE COMPOSITION AND PHOTOELECTRIC CONVERTER USING SAME FUJIKURA LTD (JP) 2011-03-16 EP disclosed
US-20100326500-A1 ELECTROLYTE COMPOSITION AND PHOTOELECTRIC CONVERSION ELEMENT USING SAME FUJIKURA LTD (JP) 2010-12-30 US disclosed
US-20100319762-A1 ELECTROLYTE COMPOSITION AND PHOTOELECTRIC CONVERSION ELEMENT USING SAME FUJIKURA LTD (JP) 2010-12-23 US disclosed
EP-2204876-A1 Electrolyte composition and photoelectric conversion element using same Fujikura, Ltd. (JP) 2010-07-07 EP disclosed
EP-2204875-A1 Electrolyte composition and photoelectric conversion element using same Fujikura, Ltd. (JP) 2010-07-07 EP disclosed
US-20080003288-A1 Responsive microgel and methods related thereto SUPRATEK PHARMA INC. (CA) 2008-01-03 US disclosed
US-7204997-B2 Responsive microgel and methods related thereto SUPRATEK PHARMA INC. (CA) 2007-04-17 US disclosed
EP-1655799-A1 ELECTROLYTE COMPOSITION AND PHOTOELECTRIC CONVERTER USING SAME Fujikura Ltd. (JP) 2006-05-10 EP disclosed
US-20060076051-A1 Electrolyte composition and photoelectric conversion element using same FUJIKURA LTD. 2006-04-13 US disclosed
EP-1478403-A1 RESPONSIVE MICROGEL AND METHODS RELATED THERETO SUPRATEK PHARMA, INC. (CA) 2004-11-24 EP disclosed
US-20030152623-A1 Responsive microgel and methods related thereto SUPRATEK PHARMA INC. (CA) 2003-08-14 US disclosed
WO-2003063909-A1 RESPONSIVE MICROGEL AND METHODS RELATED THERETO SUPRATEK PHARMA INC. (US) 2003-08-07 WO disclosed