Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2556623 | 0.92 | POLB (0.41) | NPSR1HPGDKMT2AKCNN4 | |
| SCHEMBL15331113 | 0.92 | HPGD (0.39) | NPSR1HPGDKMT2AKCNN4PTGS2 | |
| SCHEMBL2556378 | 0.90 | HPGD (0.36) | CNR1HPGDKMT2AKCNN4RIPK1 | |
| SCHEMBL2555081 | 0.87 | GAA (0.38) | GAANPSR1CNR1HPGDKMT2A | |
| SCHEMBL2558355 | 0.86 | MAPT (0.38) | NPSR1HPGDKMT2AKCNN4 | |
| SCHEMBL2560002 | 0.86 | TMEM97 (0.37) | GAAHPGDKMT2AKCNN4RIPK1 | |
| SCHEMBL2557821 | 0.86 | MAPT (0.42) | KMT2APTGS2 | |
| SCHEMBL15329895 | 0.84 | KMT2A (0.39) | HPGDKMT2AKCNN4RIPK1 | |
| SCHEMBL29950987 | 0.84 | KCNN4 (0.42) | HPGDKMT2AKCNN4 | |
| SCHEMBL15331264 | 0.84 | PTGER1 (0.35) | HPGDKMT2AKCNN4PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |