Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 5/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15332956 | 0.87 | NPC1 (0.50) | ALDH1A1NPC1RAB9AALOX5SLC2A1 | |
| SCHEMBL15331020 | 0.86 | MEN1 (0.51) | ALDH1A1NPC1RAB9ARPS6KA3CHEK2 | |
| SCHEMBL15332432 | 0.85 | ALDH1A1 (0.42) | ALDH1A1NPC1RAB9ARPS6KA3CHEK2 | |
| SCHEMBL29951865 | 0.82 | NPC1 (0.52) | ALDH1A1NPC1RAB9AALOX5SMN1; SMN2 | |
| SCHEMBL5421256 | 0.82 | ALDH1A1 (0.63) | ALDH1A1NPC1RAB9AALOX5SLC2A1 | |
| SCHEMBL15332593 | 0.82 | SLC2A1 (0.51) | ALDH1A1NPC1RAB9ASLC2A1SMN1; SMN2 | |
| SCHEMBL29956631 | 0.81 | NPC1 (0.51) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL15331325 | 0.79 | RAB9A (0.65) | ALDH1A1NPC1RAB9AALOX5SMN1; SMN2 | |
| SCHEMBL15332057 | 0.76 | ALDH1A1 (0.46) | ALDH1A1NPC1RAB9ASLC2A1SMN1; SMN2 | |
| SCHEMBL29956421 | 0.73 | PRNP (0.55) | ALDH1A1NPC1RAB9AALOX5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |