Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2558012 | 0.87 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2JAK2TYK2 | |
| SCHEMBL15330666 | 0.85 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2PARP1MAPTPIK3CA | |
| SCHEMBL5246863 | 0.82 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2HTR2CPARP1MAPT | |
| SCHEMBL22542014 | 0.82 | PIK3CA (0.35) | ALDH1A1SMN1; SMN2HTR2CPARP1MAPT | |
| SCHEMBL4944470 | 0.81 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HTR2CMAPT | |
| SCHEMBL20883564 | 0.78 | HTR2C (0.34) | ALDH1A1SMN1; SMN2HTR2CPARP1MAPT | |
| SCHEMBL5242045 | 0.77 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2PARP1MAPTGLA | |
| SCHEMBL23235276 | 0.76 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2560082 | 0.74 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2MAPTJAK2 | |
| SCHEMBL18876516 | 0.74 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |