Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | USP7 | Q93009 | 2/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 7/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2556390 | 0.83 | ERN1 (0.47) | ERN1ALDH1A1SMN1; SMN2POLBHPGD | |
| SCHEMBL2557528 | 0.83 | KDM4E (0.44) | ALDH1A1HDAC4HDAC8SMN1; SMN2POLB | |
| SCHEMBL15332234 | 0.82 | AMY1A (0.49) | ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL15332409 | 0.78 | DCUN1D1 (0.48) | ERN1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL2558953 | 0.77 | PRMT1 (0.40) | ERN1ALDH1A1SMN1; SMN2POLBHPGD | |
| SCHEMBL2556371 | 0.75 | TYR (0.43) | ERN1ALDH1A1HDAC8HPGDTYR | |
| SCHEMBL2554665 | 0.75 | ALDH1A1 (0.46) | ERN1ALDH1A1HPGD | |
| SCHEMBL15330739 | 0.74 | KDM4E (0.49) | ERN1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL15333373 | 0.74 | ESR1 (0.44) | ERN1ALDH1A1POLB | |
| SCHEMBL2561480 | 0.72 | FGFR1 (0.45) | ERN1ALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |