Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330479 | 0.90 | HPGD (0.36) | KCNN4HPGDKMT2ANPSR1HSD17B10 | |
| SCHEMBL15330760 | 0.86 | SMN1; SMN2 (0.46) | HPGDKMT2ANPSR1SMN1; SMN2NPC1 | |
| SCHEMBL15329572 | 0.86 | KCNN4 (0.40) | KCNN4HPGDKMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL15330129 | 0.85 | NPSR1 (0.38) | HPGDKMT2ANPSR1HSD17B10SMN1; SMN2 | |
| SCHEMBL2553923 | 0.84 | L3MBTL1 (0.38) | NPC1RAB9A | |
| SCHEMBL15330838 | 0.84 | NPSR1 (0.35) | HPGDNPSR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL20578432 | 0.82 | HPGD (0.46) | KCNN4HPGDKMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL15330493 | 0.82 | PDE4A (0.41) | HPGDNPSR1HSD17B10SMN1; SMN2NPC1 | |
| SCHEMBL15330119 | 0.81 | KMT2A (0.42) | KCNN4HPGDKMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL29953708 | 0.80 | SMN1; SMN2 (0.47) | HPGDKMT2ANPSR1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |