Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956741 | 0.88 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1MAPK1L3MBTL1LMNA | |
| SCHEMBL15330993 | 0.88 | MAPT (0.41) | SMN1; SMN2ALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL15331454 | 0.87 | KMT2A (0.47) | SMN1; SMN2ALDH1A1MAPK1LMNAMAPT | |
| SCHEMBL15332734 | 0.87 | MAPT (0.41) | SMN1; SMN2ALDH1A1MAPK1LMNAMAPT | |
| SCHEMBL29952221 | 0.87 | KHK (0.38) | SMN1; SMN2ALDH1A1MAPK1L3MBTL1LMNA | |
| SCHEMBL15331734 | 0.85 | MAPT (0.40) | SMN1; SMN2ALDH1A1MAPK1L3MBTL1LMNA | |
| SCHEMBL15330859 | 0.85 | MAPT (0.44) | SMN1; SMN2ALDH1A1MAPK1LMNAMAPT | |
| SCHEMBL15329559 | 0.85 | NPBWR1 (0.42) | SMN1; SMN2ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL15330213 | 0.84 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1MAPK1LMNAMAPT | |
| SCHEMBL29955028 | 0.84 | GAA (0.45) | SMN1; SMN2ALDH1A1MAPK1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |