Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330508 | 0.91 | PTGS2 (0.47) | PTGS2ALDH1A1AHRMEN1THRB | |
| SCHEMBL15331132 | 0.91 | PTGS2 (0.48) | PTGS2ALDH1A1KDM4EGLAGAA | |
| SCHEMBL7797094 | 0.88 | PTGS2 (0.55) | PTGS2AHR | |
| SCHEMBL15332926 | 0.88 | PTGS2 (0.39) | PTGS2PARP1PARP3ALDH1A1KDM4E | |
| SCHEMBL15331173 | 0.86 | PARP1 (0.43) | PTGS2PARP1PARP3ALDH1A1KDM4E | |
| SCHEMBL15330182 | 0.86 | SMN1; SMN2 (0.55) | PTGS2ALDH1A1KDM4EGLAGAA | |
| SCHEMBL15332995 | 0.85 | KDM4E (0.45) | PTGS2ALDH1A1KDM4EGLAGAA | |
| SCHEMBL2561607 | 0.85 | PTGS2 (0.44) | PTGS2ALDH1A1KDM4EGLAGAA | |
| SCHEMBL15332244 | 0.85 | ALDH1A1 (0.46) | PTGS2ALDH1A1KDM4EGLAGAA | |
| SCHEMBL2560887 | 0.84 | MEN1 (0.47) | PTGS2ALDH1A1KDM4EGAAAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |