Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 16/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 7/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CASP6 | P55212 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | APEX1 | P27695 | 3/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2557989 | 0.84 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2POLBL3MBTL1CTDSP1 | |
| SCHEMBL2561259 | 0.81 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2POLBL3MBTL1CTDSP1 | |
| SCHEMBL2559607 | 0.81 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2POLBL3MBTL1CTDSP1 | |
| SCHEMBL11494573 | 0.71 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2HTTLMNARAB9A | |
| SCHEMBL2551652 | 0.68 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2POLBL3MBTL1CTDSP1 | |
| SCHEMBL2558523 | 0.67 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2POLBL3MBTL1CTDSP1 | |
| SCHEMBL24553547 | 0.67 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2POLBL3MBTL1CTDSP1 | |
| SCHEMBL24553546 | 0.67 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2POLBL3MBTL1CTDSP1 | |
| SCHEMBL11847514 | 0.64 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2POLBL3MBTL1CTDSP1 | |
| SCHEMBL2560617 | 0.64 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2POLBL3MBTL1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |