Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.39 |
| ▸ | CASP6 | P55212 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | APEX1 | P27695 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2559607 | 0.80 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2POLBL3MBTL1CTDSP1 | |
| SCHEMBL2558341 | 0.71 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2POLBL3MBTL1CTDSP1 | |
| SCHEMBL2557989 | 0.71 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2POLBL3MBTL1CTDSP1 | |
| SCHEMBL2558791 | 0.69 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2POLBL3MBTL1CTDSP1 | |
| SCHEMBL2561259 | 0.69 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2POLBL3MBTL1CTDSP1 | |
| SCHEMBL2555988 | 0.68 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2POLBL3MBTL1CTDSP1 | |
| SCHEMBL15330935 | 0.68 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2POLBL3MBTL1CTDSP1 | |
| SCHEMBL21227822 | 0.68 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2POLBL3MBTL1CTDSP1 | |
| SCHEMBL15332496 | 0.65 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2POLBL3MBTL1CTDSP1 | |
| SCHEMBL14232240 | 0.64 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2POLBL3MBTL1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |