Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.61 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.51 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 2/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18805419 | 0.76 | ERN1 (0.51) | ERN1CYP2A6ALDH1A1PTP4A3HDAC2 | |
| SCHEMBL2531595 | 0.76 | CYP2A6 (0.61) | CYP2A6IMPDH2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL15330645 | 0.76 | CYP2A6 (0.53) | CYP2A6IMPDH2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL12767810 | 0.76 | ERN1 (1.00) | ERN1CYP2A6HDAC2 | |
| SCHEMBL15330738 | 0.76 | CYP2A6 (0.53) | ERN1CYP2A6IMPDH2ALDH1A1CYP1A2 | |
| SCHEMBL15330461 | 0.76 | CYP2A6 (0.53) | ERN1CYP2A6IMPDH2ALDH1A1CYP1A2 | |
| SCHEMBL15331971 | 0.74 | ERN1 (0.59) | ERN1CYP2A6IMPDH2ALDH1A1CYP1A2 | |
| SCHEMBL15333332 | 0.73 | HTR1D (0.56) | ERN1CYP2A6IMPDH2ALDH1A1CYP1A2 | |
| SCHEMBL15330071 | 0.73 | ICMT (0.59) | ERN1CYP2A6IMPDH2ALDH1A1CYP1A2 | |
| SCHEMBL13129269 | 0.72 | ERN1 (0.56) | ERN1CYP2A6HDAC2MAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |