Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.53 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.51 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 3/20 | 0.47 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.44 |
| ▸ | PIM1 | P11309 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NMT2 | O60551 | 1/20 | 0.41 |
| ▸ | NMT1 | P30419 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330738 | 0.83 | CYP2A6 (0.53) | CYP2A6IMPDH2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL15330461 | 0.83 | CYP2A6 (0.53) | CYP2A6IMPDH2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL15330071 | 0.82 | ICMT (0.59) | CYP2A6IMPDH2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL2531595 | 0.80 | CYP2A6 (0.61) | CYP2A6IMPDH2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL15330072 | 0.79 | ALDH1A1 (0.56) | CYP2A6IMPDH2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL9231963 | 0.78 | ICMT (0.55) | CYP2A6IMPDH2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL12680425 | 0.78 | CYP2A6 (0.50) | CYP2A6IMPDH2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL15330951 | 0.76 | ERN1 (0.61) | CYP2A6IMPDH2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL1094048 | 0.75 | ALDH1A1 (0.63) | CYP2A6IMPDH2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL3459128 | 0.74 | CYP2A6 (0.46) | CYP2A6IMPDH2ALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |