Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.49 |
| ▸ | RXRB | P28702 | 4/20 | 0.49 |
| ▸ | RXRG | P48443 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 6/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18002272 | 0.85 | RXRA (0.40) | RXRARXRBRXRGCES2CNR1 | |
| SCHEMBL15331511 | 0.81 | HCAR1 (0.43) | CES2 | |
| SCHEMBL17048588 | 0.79 | RXRA (0.72) | RXRARXRBRXRGDHODHCES2 | |
| SCHEMBL15332306 | 0.79 | CA12 (0.47) | KDM4EMEN1ALDH1A1KMT2ADHODH | |
| SCHEMBL2563115 | 0.78 | RXRA (0.47) | RXRARXRBRXRGKDM4EMEN1 | |
| SCHEMBL2557141 | 0.78 | TPMT (0.48) | RXRARXRBKDM4EMEN1KMT2A | |
| SCHEMBL2554759 | 0.78 | KDM4E (0.35) | KDM4EMEN1ALDH1A1KMT2ADHODH | |
| SCHEMBL2554127 | 0.77 | RXRA (0.64) | RXRARXRBRXRGALDH1A1DHODH | |
| SCHEMBL3082270 | 0.76 | RXRA (0.72) | RXRARXRBRXRGDHODHCES2 | |
| SCHEMBL2562291 | 0.74 | RXRA (0.49) | RXRAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |