SCHEMBL15334635

SCHEMBL15334635

CCC(CC)(c1ccc(C)cc1)c1ccc(OS(=O)(=O)C2=CC(=[N+]=[N-])C(=O)c3ccccc32)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
VDR P11473 1/20 0.33
HPGD P15428 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
DHODH Q02127 1/20 0.32
NPC1 O15118 1/20 0.32
LMNA P02545 1/20 0.32
MAPK1 P28482 1/20 0.32
CASP3 P42574 1/20 0.32
RAB9A P51151 1/20 0.32
ATM Q13315 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
ALDH1A1 P00352 3/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3141815 0.96 NPC1 (0.34) NPC1LMNAMAPK1CASP3RAB9A
SCHEMBL15334631 0.91 CES2 (0.34) CES2CES1VDRHPGDNPSR1
SCHEMBL3401243 0.90 NPC1 (0.30) NPC1LMNAMAPK1CASP3RAB9A
SCHEMBL13380590 0.88 NPC1 (0.31) NPC1LMNAMAPK1CASP3RAB9A
SCHEMBL3145451 0.86 NPC1 (0.36) NPC1LMNAMAPK1CASP3RAB9A
SCHEMBL13380593 0.85
SCHEMBL11973248 0.81 SMN1; SMN2 (0.36) NPC1LMNAMAPK1CASP3RAB9A
SCHEMBL11973182 0.81 NR3C2 (0.35) NPC1LMNACASP3RAB9ASMN1; SMN2
SCHEMBL13155965 0.81 ALDH1A1 (0.32) HPGDNPC1LMNAMAPK1CASP3
SCHEMBL3397798 0.81 NPC1 (0.32) NPC1LMNAMAPK1CASP3RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8563215-B2 Diazonaphthoquinonesulfonic acid bisphenol derivative useful in photo lithographic sub micron patterning and a process for preparation thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2013-10-22 US disclosed