Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.49 |
| ▸ | CDK8 | P49336 | 8/20 | 0.40 |
| ▸ | CCNC | P24863 | 6/20 | 0.40 |
| ▸ | CDK19 | Q9BWU1 | 5/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | CLK3 | P49761 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CCND3 | P30281 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15331887 | 0.92 | CYP11B2 (0.47) | CYP11B2CDK8CCNCCDK19CDC7 | |
| SCHEMBL26683815 | 0.81 | CRBN (0.49) | CYP11B2CDK8CCNCCDK19CREBBP | |
| SCHEMBL30449846 | 0.81 | CRBN (0.49) | CYP11B2CDK8CCNCCDK19CREBBP | |
| SCHEMBL15344908 | 0.79 | CYP11B2 (0.47) | CYP11B2CDC7CREBBPBRD4DYRK3 | |
| SCHEMBL15344945 | 0.77 | CYP11B2 (0.48) | CYP11B2CDC7CREBBPBRD4DYRK3 | |
| SCHEMBL16874175 | 0.75 | HTR3E (0.51) | CYP11B2CDK8 | |
| SCHEMBL31330017 | 0.75 | HTR3E (0.51) | CYP11B2CDK8 | |
| SCHEMBL15340925 | 0.75 | CYP11B2 (0.44) | CYP11B2CDC7CREBBPBRD4DYRK3 | |
| Hydrochloric Acid SCHEMBL2798908 | 0.74 | HTR3E (0.50) | CYP11B2CDK8 | |
| SCHEMBL15340920 | 0.73 | CYP11B2 (0.45) | CYP11B2CDC7CREBBPBRD4DYRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096586-B2 | Therapeutic compounds | GILEAD SCIENCES, INC. (US) | 2015-08-04 | — | — | US | disclosed |
| US-20130281434-A1 | THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2013-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281434-A1 | THERAPEUTIC COMPOUNDS | NFATC1, FURIN, CD4 | CYP11B2 21/4885CDK8 856/4885CCNC 328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.