Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.61 |
| ▸ | CTSK | P43235 | 5/20 | 0.61 |
| ▸ | REN | P00797 | 6/20 | 0.59 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.50 |
| ▸ | NPY1R | P25929 | 2/20 | 0.50 |
| ▸ | NPY4R | P50391 | 2/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2801456 | 0.89 | CTSS (0.66) | CTSSCTSKRENACECTSL | |
| SCHEMBL2803528 | 0.89 | CTSS (0.66) | CTSSCTSKRENACECTSL | |
| SCHEMBL31093990 | 0.87 | CTSS (0.65) | CTSSCTSKRENCTSLCTSB | |
| SCHEMBL13413393 | 0.87 | CTSS (0.65) | CTSSCTSKRENCTSLCTSB | |
| SCHEMBL3469005 | 0.86 | CTSS (0.69) | CTSSCTSKRENACECTSL | |
| SCHEMBL4024913 | 0.86 | CTSS (0.69) | CTSSCTSKRENACECTSL | |
| SCHEMBL4024908 | 0.86 | CTSS (0.69) | CTSSCTSKRENACECTSL | |
| SCHEMBL3469003 | 0.86 | CTSS (0.69) | CTSSCTSKRENACECTSL | |
| SCHEMBL6803377 | 0.85 | CTSS (0.57) | CTSSCTSKRENACECTSL | |
| SCHEMBL6803380 | 0.85 | CTSS (0.57) | CTSSCTSKRENACECTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169295-B2 | Macrocycles and macrocycle stabilized peptides | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-10-27 | — | — | US | disclosed |
| EP-2627662-B1 | METHODS FOR PREPARING MACROCYCLES AND MACROCYCLE STABILIZED PEPTIDES | BRISTOL MYERS SQUIBB CO (US) | 2015-09-16 | — | — | EP | disclosed |
| US-20130281657-A1 | MACROCYCLES AND MACROCYCLE STABILIZED PEPTIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281657-A1 | MACROCYCLES AND MACROCYCLE STABILIZED PEPTIDES | PTMS, VIP, MTPN | CTSS 176/4885CTSK 492/4885REN 1517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.