Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.57 |
| ▸ | CTSK | P43235 | 5/20 | 0.57 |
| ▸ | REN | P00797 | 3/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 3/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6803377 | 1.00 | CTSS (0.57) | CTSSCTSKRENPPARGPPARA | |
| SCHEMBL6808534 | 0.92 | REN (0.63) | CTSSCTSKRENPPARGPPARA | |
| SCHEMBL6808536 | 0.92 | REN (0.63) | CTSSCTSKRENPPARGPPARA | |
| SCHEMBL4714186 | 0.92 | PPARG (0.58) | CTSSCTSKRENPPARGPPARA | |
| SCHEMBL500110 | 0.92 | PPARG (0.58) | CTSSCTSKRENPPARGPPARA | |
| SCHEMBL500111 | 0.92 | PPARG (0.58) | CTSSCTSKRENPPARGPPARA | |
| SCHEMBL3477645 | 0.91 | CTSS (0.58) | CTSSCTSKPPARGPPARACTSL | |
| SCHEMBL2801456 | 0.86 | CTSS (0.66) | CTSSCTSKRENPPARGPPARA | |
| SCHEMBL2803528 | 0.86 | CTSS (0.66) | CTSSCTSKRENPPARGPPARA | |
| SCHEMBL14552051 | 0.85 | PPARG (0.54) | CTSSCTSKPPARGPPARACTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040167183-A1 | Phenethylamino sulfamic acids | THE PROCTER & GAMBLE COMPANY | 2004-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167183-A1 | Phenethylamino sulfamic acids | PTPRM, PTPRS, PTPRE | CTSS 1861/4885CTSK 2457/4885REN 343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.