Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6173075 | 0.74 | — | — | |
| SCHEMBL3721021 | 0.70 | TRPA1 (0.31) | TSHR | |
| SCHEMBL6508592 | 0.67 | — | — | |
| SCHEMBL2328402 | 0.67 | — | — | |
| SCHEMBL20258303 | 0.66 | — | — | |
| SCHEMBL1133791 | 0.65 | — | — | |
| SCHEMBL10406818 | 0.61 | — | — | |
| SCHEMBL1992581 | 0.61 | — | — | |
| SCHEMBL11203651 | 0.61 | — | — | |
| Isobutanol SCHEMBL4243770 | 0.61 | TSHR (0.53) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8569484-B2 | Heterocyclic urea derivatives and methods of use thereof | ASTRAZENECA AB (SE) | 2013-10-29 | — | — | US | claimed |