Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | XBP1 | P17861 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3089832 | 0.83 | ALDH1A1 (0.45) | ALDH1A1TSHRPLA2G2CCA2CA1 | |
| SCHEMBL28968914 | 0.83 | ALDH1A1 (0.45) | ALDH1A1TSHRPLA2G2CCA2CA1 | |
| SCHEMBL12944323 | 0.83 | ALDH1A1 (0.43) | ALDH1A1TSHRPLA2G2CLMNAHTT | |
| SCHEMBL15344686 | 0.82 | CA1 (0.33) | ALDH1A1TSHRLMNAHTTNPSR1 | |
| SCHEMBL8193095 | 0.82 | ALDH1A1 (0.43) | ALDH1A1TSHRLMNAHTTNPSR1 | |
| SCHEMBL384396 | 0.82 | ALDH1A1 (0.42) | ALDH1A1TSHRPLA2G2CLMNAHTT | |
| SCHEMBL1764915 | 0.82 | ALDH1A1 (0.42) | ALDH1A1TSHRLMNAHTTNPSR1 | |
| SCHEMBL1764913 | 0.82 | ALDH1A1 (0.42) | ALDH1A1TSHRLMNAHTTNPSR1 | |
| SCHEMBL15627953 | 0.81 | AAK1 (0.52) | ALDH1A1TSHRLMNAHTTNPSR1 | |
| SCHEMBL29255200 | 0.81 | ALDH1A1 (0.42) | ALDH1A1TSHRLMNAHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187419-B2 | Intermediates of sitagliptin and preparation process thereof | ZHEJIANG HISOAR PHARMACEUTICAL CO., LTD. (CN) | 2015-11-17 | — | — | US | disclosed |
| US-20130281695-A1 | INTERMEDIATES OF SITAGLIPTIN AND PREPARATION PROCESS THEREOF | ZHEJIANG HISOAR PHARMACEUTICAL CO., LTD. (CN) | 2013-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281695-A1 | INTERMEDIATES OF SITAGLIPTIN AND PREPARATION PROCESS THEREOF | DPP4, DPP9, DPP3 | ALDH1A1 2403/4885TSHR 3902/4885PLA2G2C 1851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.