Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | PLG | P00747 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA3 | P07451 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26656786 | 0.97 | — | — | |
| SCHEMBL15345219 | 0.90 | — | — | |
| SCHEMBL9236583 | 0.79 | LMNA (0.59) | PAOXLMNAKMT2ATHRBMEN1 | |
| SCHEMBL8427109 | 0.77 | PAOX (0.54) | PAOXLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL22756799 | 0.77 | CES2 (0.59) | KMT2AMEN1ALDH1A1ALOX15TSHR | |
| SCHEMBL3160273 | 0.77 | CES2 (0.59) | KMT2AMEN1ALDH1A1ALOX15TSHR | |
| SCHEMBL13636538 | 0.77 | CES2 (0.59) | KMT2AMEN1ALDH1A1ALOX15TSHR | |
| SCHEMBL7937351 | 0.77 | CES2 (0.59) | KMT2AMEN1ALDH1A1ALOX15TSHR | |
| SCHEMBL25753802 | 0.77 | CES2 (0.59) | KMT2AMEN1ALDH1A1ALOX15TSHR | |
| SCHEMBL10937134 | 0.77 | CES2 (0.59) | KMT2AMEN1ALDH1A1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130280766-A1 | HYBRID POLYKETIDE SYNTHASES | THE REGENTS OF THE UNVERSITY OF CALIFORNIA (US) | 2013-10-24 | — | — | US | disclosed |