Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1738987 | 0.88 | TSHR (0.54) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5830541 | 0.85 | CHRNB2 (0.46) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| Ethylene Glycol SCHEMBL7708268 | 0.82 | LMNA (0.48) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL2059697 | 0.77 | TSHR (0.50) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL31296577 | 0.77 | TSHR (0.50) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5721434 | 0.77 | TSHR (0.50) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL2746089 | 0.77 | TSHR (0.50) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL2136691 | 0.77 | TSHR (0.50) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5721317 | 0.77 | TSHR (0.50) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL2139712 | 0.77 | TSHR (0.50) | LMNACHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2657281-A1 | Rubber Compositions | Cytec Surface Specialties Germany GmbH (DE) | 2013-10-30 | — | — | EP | claimed |