Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1308171 | 0.82 | LMNA (0.49) | POLBTDP1SMN1; SMN2GAALMNA | |
| SCHEMBL2778055 | 0.82 | LMNA (0.49) | POLBTDP1SMN1; SMN2GAALMNA | |
| SCHEMBL5028546 | 0.76 | TDP1 (0.51) | POLBKDM4ETDP1SMN1; SMN2GAA | |
| SCHEMBL441192 | 0.73 | POLB (0.38) | POLBKDM4ETDP1SMN1; SMN2LMNA | |
| SCHEMBL1263987 | 0.73 | TSHR (0.52) | POLBKDM4ETDP1SMN1; SMN2GAA | |
| SCHEMBL28003480 | 0.72 | TDP1 (0.50) | POLBKDM4ETDP1SMN1; SMN2GAA | |
| SCHEMBL9724589 | 0.72 | TDP1 (0.50) | POLBKDM4ETDP1SMN1; SMN2GAA | |
| Bicarbonate SCHEMBL16751853 | 0.72 | MAOB (0.54) | POLBKDM4ETDP1SMN1; SMN2LMNA | |
| SCHEMBL27165062 | 0.72 | TSHR (0.51) | POLBKDM4ETDP1SMN1; SMN2GAA | |
| SCHEMBL3257562 | 0.72 | POLB (0.40) | POLBKDM4ETDP1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382369-B2 | Rubber-modified vinyl-based graft copolymer, and thermoplastic resin composition including the same | CHEIL INDUSTRIES INC. (KR) | 2016-07-05 | — | — | US | disclosed |
| US-20130289198-A1 | Rubber-Modified Vinyl-Based Graft Copolymer, and Thermoplastic Resin Composition Including the Same | LOTTE ADVANCED MATERIALS CO., LTD. (KR) | 2013-10-31 | — | — | US | disclosed |