Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15345921 | 1.00 | UGT2B7 (0.33) | UGT2B7LANCL2 | |
| SCHEMBL3336877 | 0.82 | LANCL2 (0.32) | UGT2B7LANCL2 | |
| SCHEMBL3001106 | 0.82 | LANCL2 (0.32) | UGT2B7LANCL2 | |
| SCHEMBL3010731 | 0.82 | LANCL2 (0.32) | UGT2B7LANCL2 | |
| SCHEMBL3001104 | 0.82 | LANCL2 (0.32) | UGT2B7LANCL2 | |
| SCHEMBL17822576 | 0.82 | LANCL2 (0.32) | UGT2B7LANCL2 | |
| SCHEMBL9287929 | 0.82 | LANCL2 (0.32) | UGT2B7LANCL2 | |
| SCHEMBL3336886 | 0.82 | LANCL2 (0.32) | UGT2B7LANCL2 | |
| SCHEMBL3001100 | 0.82 | LANCL2 (0.32) | UGT2B7LANCL2 | |
| SCHEMBL15355842 | 0.79 | L3MBTL1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9499558-B2 | Compounds and methods for treating HIV | PURDUE RESEARCH FOUNDATION (US) | 2016-11-22 | — | — | US | disclosed |
| US-20150225414-A1 | COMPOUNDS AND METHODS FOR TREATING HIV | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-08-13 | — | — | US | disclosed |
| US-9024038-B2 | Compunds and methods for treating HIV | PURDUE RESEARCH FOUNDATION (US) | 2015-05-05 | — | — | US | disclosed |
| US-20130289067-A1 | COMPOUNDS AND METHODS FOR TREATING HIV | PURDUE RESEARCH FOUNDATION | 2013-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150225414-A1 | COMPOUNDS AND METHODS FOR TREATING HIV | SERPINB1, HPN, DNPEP | UGT2B7 1542/4885LANCL2 4405/4885 |
| US-20130289067-A1 | COMPOUNDS AND METHODS FOR TREATING HIV | SERPINB1, HPN, DNPEP | UGT2B7 1542/4885LANCL2 4405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.