Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 9/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | HCK | P08631 | 1/20 | 0.40 |
| ▸ | ROS1 | P08922 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15345967 | 1.00 | CHRNB4 (0.50) | CHRNB4CHRNA3KDM1AMAOBMEN1 | |
| SCHEMBL14882006 | 0.84 | KDM1A (0.65) | KDM1AMAOBCNR2EPHX2EGFR | |
| SCHEMBL14882007 | 0.84 | KDM1A (0.65) | KDM1AMAOBCNR2EPHX2EGFR | |
| SCHEMBL15355740 | 0.80 | KDM1A (0.59) | CHRNB4CHRNA3KDM1AMAOBCNR2 | |
| SCHEMBL1290434 | 0.80 | KDM1A (0.59) | CHRNB4CHRNA3KDM1AMAOBCNR2 | |
| SCHEMBL1290435 | 0.80 | KDM1A (0.59) | CHRNB4CHRNA3KDM1AMAOBCNR2 | |
| Hydrochloric Acid SCHEMBL1290665 | 0.79 | KDM1A (0.57) | CHRNB4CHRNA3KDM1AMAOBCNR2 | |
| Hydrochloric Acid SCHEMBL1290666 | 0.79 | KDM1A (0.57) | CHRNB4CHRNA3KDM1AMAOBCNR2 | |
| SCHEMBL12500007 | 0.78 | CHRNB4 (0.46) | CHRNB4CHRNA3KDM1AMAOBMEN1 | |
| SCHEMBL12500010 | 0.78 | CHRNB4 (0.46) | CHRNB4CHRNA3KDM1AMAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160000768-A1 | CYCLOPROPYLAMINE INHIBITORS OF OXIDASES | ORYZON GENOMICS S.A. (ES) | 2016-01-07 | — | — | US | disclosed |
| US-9061966-B2 | Cyclopropylamine inhibitors of oxidases | ORYZON GENOMICS S.A. (ES) | 2015-06-23 | — | — | US | disclosed |
| US-20130289076-A1 | CYCLOPROPYLAMINE INHIBITORS OF OXIDASES | ORYZON GENOMICS S.A. (ES) | 2013-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160000768-A1 | CYCLOPROPYLAMINE INHIBITORS OF OXIDASES | PPOX, MAOB, MAOA | CHRNB4 1351/4885CHRNA3 1323/4885KDM1A 828/4885 |
| US-20130289076-A1 | CYCLOPROPYLAMINE INHIBITORS OF OXIDASES | PPOX, MAOB, MAOA | CHRNB4 1351/4885CHRNA3 1323/4885KDM1A 828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.