Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | SCN4A | P35499 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD1 | P21728 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15346432 | 1.00 | ALDH1A1 (0.58) | ALDH1A1SCN8ASMN1; SMN2ALOX15KDM4E | |
| SCHEMBL15346302 | 1.00 | ALDH1A1 (0.58) | ALDH1A1SCN8ASMN1; SMN2ALOX15KDM4E | |
| SCHEMBL15346418 | 0.96 | ALDH1A1 (0.64) | ALDH1A1SCN8ASMN1; SMN2ALOX15KDM4E | |
| SCHEMBL16446046 | 0.92 | ALDH1A1 (0.50) | ALDH1A1SCN8ASMN1; SMN2ALOX15KDM4E | |
| SCHEMBL15346343 | 0.91 | ALDH1A1 (0.52) | ALDH1A1SCN8ASMN1; SMN2ALOX15KDM4E | |
| SCHEMBL15346289 | 0.89 | ALDH1A1 (0.56) | ALDH1A1SCN8ASMN1; SMN2ALOX15KDM4E | |
| SCHEMBL15346263 | 0.85 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2ALOX15KDM4EL3MBTL1 | |
| SCHEMBL16445466 | 0.84 | ALDH1A1 (0.45) | ALDH1A1SCN8ASMN1; SMN2ALOX15KDM4E | |
| SCHEMBL1195765 | 0.82 | KDM4E (0.62) | ALDH1A1SCN8ASMN1; SMN2KDM4EHTR1A | |
| SCHEMBL1195323 | 0.82 | KDM4E (0.62) | ALDH1A1SCN8ASMN1; SMN2KDM4EHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841347-B2 | Derivatives of aminoalkanols, method of obtaining of aminoalkanols and their use | UNIWERSYTET JAGIELLONSKI (PL) | 2014-09-23 | — | — | US | claimed |
| US-8633251-B2 | Derivatives of aminoalkanols, method of obtaining of aminoalkanols and their use | UNIWERSYTET JAGIELLONSKI (PL) | 2014-01-21 | — | — | US | claimed |
| US-20130289118-A1 | DERIVATIVES OF AMINOALKANOLS, METHOD OF OBTAINING OF AMINOALKANOLS AND THEIR USE | UNIWERSYTET JAGIELLONSKI (PL) | 2013-10-31 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130289118-A1 | DERIVATIVES OF AMINOALKANOLS, METHOD OF OBTAINING OF AMINOALKANOLS AND THEIR USE | SCN1A, SCN3A, ACHE | ALDH1A1 461/4885SCN8A 7/4885SMN1; SMN2 812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.