Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15364178 | 0.75 | HPGD (0.40) | PKMALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL15364602 | 0.73 | GAA (0.39) | PKMALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL15364605 | 0.73 | GAA (0.39) | PKMALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL14905763 | 0.69 | KDM4E (0.42) | PKMALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL1204664 | 0.69 | KDM4E (0.42) | PKMALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL15364494 | 0.68 | CES2 (0.44) | PKMALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL15364152 | 0.68 | TDP1 (0.50) | PKMSMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL18412118 | 0.67 | KDM4E (0.44) | ALDH1A1SMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL16237782 | 0.67 | TDP1 (0.39) | PKMALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL16237780 | 0.67 | TDP1 (0.39) | PKMALDH1A1SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9868805-B2 | Polydienes and diene copolymers having organophosphine functionality | BRIDGESTONE CORPORATION (JP) | 2018-01-16 | — | — | US | disclosed |
| EP-2844678-B1 | POLYDIENES AND DIENE COPOLYMERS HAVING ORGANOPHOSPHINE FUNCTIONALITY | BRIDGESTONE CORP (JP) | 2017-02-22 | — | — | EP | disclosed |
| US-9499651-B2 | Copolymers of conjugated dienes and vinyl organophosphines prepared by anionic polymerization | BRIDGESTONE CORPORATION (JP) | 2016-11-22 | — | — | US | disclosed |
| US-9127109-B2 | Preparation of functional polymers phosphorus-containing organometal initiators | BRIDGESTONE CORPORATION (JP) | 2015-09-08 | — | — | US | disclosed |
| US-20150126675-A1 | Polydienes And Diene Copolymers Having Organophosphine Functionality | BRIDGESTONE CORPORATION (JO) | 2015-05-07 | — | — | US | disclosed |
| EP-2844678-A1 | POLYDIENES AND DIENE COPOLYMERS HAVING ORGANOPHOSPHINE FUNCTIONALITY | Bridgestone Corporation (JP) | 2015-03-11 | — | — | EP | disclosed |
| US-20140275428-A1 | Copolymers Of Conjugated Dienes And Vinyl Organophosphines Prepared By Anionic Polymerization | BRIDGESTONE CORPORATION (JP) | 2014-09-18 | — | — | US | disclosed |
| US-20130296480-A1 | PREPARATION OF FUNCTIONAL POLYMERS PHOSPHORUS-CONTAINING ORGANOMETAL INITIATORS | BRIDGESTONE CORPORATION (JP) | 2013-11-07 | — | — | US | disclosed |
| WO-2013166124-A1 | POLYDIENES AND DIENE COPOLYMERS HAVING ORGANOPHOSPHINE FUNCTIONALITY | BRIDGESTONE CORPORATION (JP) | 2013-11-07 | — | — | WO | disclosed |