Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15364254 | 0.75 | PKM (0.38) | LMNAGAAALDH1A1NPC1PKM | |
| SCHEMBL15364540 | 0.73 | TLK2 (0.33) | GAAALDH1A1 | |
| SCHEMBL28139547 | 0.71 | HPGD (0.43) | HPGDLMNAPOLBELANEGAA | |
| SCHEMBL15364208 | 0.68 | GRIN1 (0.40) | POLBGAA | |
| SCHEMBL15364206 | 0.68 | GRIN1 (0.40) | POLBGAA | |
| SCHEMBL933800 | 0.67 | ALDH1A1 (0.42) | HPGDLMNAMTNR1AMTNR1BGAA | |
| SCHEMBL15364717 | 0.66 | MGLL (0.39) | ALDH1A1 | |
| SCHEMBL14448213 | 0.65 | TDP1 (0.39) | ALDH1A1 | |
| SCHEMBL9784213 | 0.64 | ALDH1A1 (0.42) | HPGDLMNAPOLBMTNR1AMTNR1B | |
| SCHEMBL15364537 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9868805-B2 | Polydienes and diene copolymers having organophosphine functionality | BRIDGESTONE CORPORATION (JP) | 2018-01-16 | — | — | US | disclosed |
| EP-2844678-B1 | POLYDIENES AND DIENE COPOLYMERS HAVING ORGANOPHOSPHINE FUNCTIONALITY | BRIDGESTONE CORP (JP) | 2017-02-22 | — | — | EP | disclosed |
| US-9499651-B2 | Copolymers of conjugated dienes and vinyl organophosphines prepared by anionic polymerization | BRIDGESTONE CORPORATION (JP) | 2016-11-22 | — | — | US | disclosed |
| US-9127109-B2 | Preparation of functional polymers phosphorus-containing organometal initiators | BRIDGESTONE CORPORATION (JP) | 2015-09-08 | — | — | US | disclosed |
| US-20150126675-A1 | Polydienes And Diene Copolymers Having Organophosphine Functionality | BRIDGESTONE CORPORATION (JO) | 2015-05-07 | — | — | US | disclosed |
| EP-2844678-A1 | POLYDIENES AND DIENE COPOLYMERS HAVING ORGANOPHOSPHINE FUNCTIONALITY | Bridgestone Corporation (JP) | 2015-03-11 | — | — | EP | disclosed |
| US-20140275428-A1 | Copolymers Of Conjugated Dienes And Vinyl Organophosphines Prepared By Anionic Polymerization | BRIDGESTONE CORPORATION (JP) | 2014-09-18 | — | — | US | disclosed |
| WO-2013166124-A1 | POLYDIENES AND DIENE COPOLYMERS HAVING ORGANOPHOSPHINE FUNCTIONALITY | BRIDGESTONE CORPORATION (JP) | 2013-11-07 | — | — | WO | disclosed |
| US-20130296480-A1 | PREPARATION OF FUNCTIONAL POLYMERS PHOSPHORUS-CONTAINING ORGANOMETAL INITIATORS | BRIDGESTONE CORPORATION (JP) | 2013-11-07 | — | — | US | disclosed |