SCHEMBL15364313

SCHEMBL15364313

Nc1ccc(OC(=O)/C=C/c2ccc(/C=C/C(=O)Oc3ccc(N)cc3)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.62
MAPT P10636 5/20 0.53
MEN1 O00255 4/20 0.53
CYP19A1 P11511 2/20 0.51
KDM4E B2RXH2 1/20 0.48
CYP1B1 Q16678 1/20 0.47
F3 P13726 1/20 0.47
RAB9A P51151 3/20 0.46
NPC1 O15118 2/20 0.46
NFKB1 P19838 2/20 0.46
NFKB2 Q00653 2/20 0.46
RELA Q04206 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
PSMD14 O00487 1/20 0.46
CRHBP P24387 1/20 0.46
CRHR2 Q13324 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
TYR P14679 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15363576 1.00 KMT2A (0.62) KMT2AMAPTMEN1CYP19A1KDM4E
SCHEMBL30775463 1.00 KMT2A (0.62) KMT2AMAPTMEN1CYP19A1KDM4E
SCHEMBL15364345 1.00 KMT2A (0.62) KMT2AMAPTMEN1CYP19A1KDM4E
SCHEMBL3229347 1.00 KMT2A (0.62) KMT2AMAPTMEN1CYP19A1KDM4E
SCHEMBL15364341 1.00 KMT2A (0.62) KMT2AMAPTMEN1CYP19A1KDM4E
SCHEMBL16024181 0.92 KMT2A (0.55) KMT2AMAPTMEN1CYP19A1KDM4E
SCHEMBL27758582 0.92 KMT2A (0.54) KMT2AMAPTMEN1CYP19A1RAB9A
SCHEMBL16024193 0.92 KMT2A (0.55) KMT2AMAPTMEN1CYP19A1KDM4E
SCHEMBL21515007 0.92 CYP19A1 (0.65) KMT2AMAPTMEN1CYP19A1KDM4E
SCHEMBL27737751 0.92 KMT2A (0.54) KMT2AMAPTMEN1CYP19A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180163135-A1 LIQUID CRYSTAL POLYMERIZED FILMS USING ALIGNMENT FILM AND POLYMERIZABLE LIQUID CRYSTAL COMPOSTION JNC CORPORATION (JP) 2018-06-14 US disclosed
US-20180163135-A1 LIQUID CRYSTAL POLYMERIZED FILMS USING ALIGNMENT FILM AND POLYMERIZABLE LIQUID CRYSTAL COMPOSTION JNC CORPORATION (JP) 2018-06-14 US disclosed
WO-2013161984-A1 DIAMINE, POLYMER, LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学工業株式会社 (JP) 2013-10-31 WO disclosed