SCHEMBL3229347

SCHEMBL3229347

Nc1ccc(C=CC(=O)Oc2ccc(N)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.62
MAPT P10636 5/20 0.53
MEN1 O00255 4/20 0.53
CYP19A1 P11511 2/20 0.51
KDM4E B2RXH2 1/20 0.48
CYP1B1 Q16678 1/20 0.47
F3 P13726 1/20 0.47
RAB9A P51151 3/20 0.46
NPC1 O15118 2/20 0.46
NFKB1 P19838 2/20 0.46
NFKB2 Q00653 2/20 0.46
RELA Q04206 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
PSMD14 O00487 1/20 0.46
CRHBP P24387 1/20 0.46
CRHR2 Q13324 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
TYR P14679 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15363576 1.00 KMT2A (0.62) KMT2AMAPTMEN1CYP19A1KDM4E
SCHEMBL15364313 1.00 KMT2A (0.62) KMT2AMAPTMEN1CYP19A1KDM4E
SCHEMBL30775463 1.00 KMT2A (0.62) KMT2AMAPTMEN1CYP19A1KDM4E
SCHEMBL15364345 1.00 KMT2A (0.62) KMT2AMAPTMEN1CYP19A1KDM4E
SCHEMBL15364341 1.00 KMT2A (0.62) KMT2AMAPTMEN1CYP19A1KDM4E
SCHEMBL16024181 0.92 KMT2A (0.55) KMT2AMAPTMEN1CYP19A1KDM4E
SCHEMBL27758582 0.92 KMT2A (0.54) KMT2AMAPTMEN1CYP19A1RAB9A
SCHEMBL16024193 0.92 KMT2A (0.55) KMT2AMAPTMEN1CYP19A1KDM4E
SCHEMBL21515007 0.92 CYP19A1 (0.65) KMT2AMAPTMEN1CYP19A1KDM4E
SCHEMBL27737751 0.92 KMT2A (0.54) KMT2AMAPTMEN1CYP19A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117348297-A Method for producing liquid crystal alignment film, method for producing liquid crystal display element, liquid crystal alignment film, and liquid crystal display element 日产化学株式会社 2024-01-05 CN disclosed
US-20100060834-A1 COPOLYIMIDE, LIQUID CRYSTAL ALIGNING LAYER COMPRISING THE SAME , AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME LG CHEM, LTD. (KR) 2010-03-11 US disclosed
WO-2008084944-A1 NEW COPOLYIMIDE, LIQUID CRYSTAL ALIGNING LAYER COMPRISING THE SAME, AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME LG CHEM, LTD. (KR) 2008-07-17 WO disclosed
WO-2007064160-A1 METHOD OF PRODUCING LIQUID CRYSTAL ALIGNING LAYER, LIQUID CRYSTAL ALIGNING LAYER PRODUCED USING THE SAME, AND LIQUID CRYSTAL DISPLAY INCLUDING LIQUID CRYSTAL ALIGNING LAYER LG CHEM. LTD. (KR) 2007-06-07 WO disclosed
US-20070128378-A1 Method of producing liquid crystal aligning layer, liquid crystal aligning layer produced using the same, and liquid crystal display including liquid crystal aligning layer LG CHEM, LTD. (KR) 2007-06-07 US disclosed
US-6689899-B2 HYDROGENATION OF THE CORRESPONDING DINITRO COMPOUNDS KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2004-02-10 US disclosed
US-6642393-B2 Such as 2,5-(dihydroxybenzenecarboxylic octane)-dibenzoate-3,3',4,4' -tetracarboxylic acid anhydride for producing polyimides or polyamic acides having low water absorption; for use in cosmetics, aeronautics, and electronics KANEKA CORPORATION (JP) 2003-11-04 US disclosed
US-20020055610-A1 Novel polyimide compositions and novel acid dianhydrides to be used therein KANEKA CORPORATION (JP) 2002-05-09 US disclosed
US-6350845-B1 POLYAMIDEIMIDE COPOLYMERS FOR NONABSORBENT HEAT RESISTANT COMPOSITIONS KANEKA CORPORATION (JP) 2002-02-26 US disclosed
US-20020019558-A1 Diamine and acid anhydride KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2002-02-14 US disclosed
US-6303742-B1 CHARACTERIZED BY A CINNAMOYL GROUP OR A DERIVED CINNAMOYL GROUP INCORPORATED THEREIN AND BY PHOTO-REACTIVITY AND HEAT-REACTIVITY WHICH ARE INHERENT IN THE CINNAMOYL GROUP. KANEKAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2001-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019558-A1 Diamine and acid anhydride CA1, ASIC1, CA4 KMT2A 679/4885MAPT 573/4885MEN1 1404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.