Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28536397 | 0.92 | HSD11B1 (0.62) | KMT2AMEN1HSD11B1KDM4EGAA | |
| SCHEMBL15363576 | 0.92 | KMT2A (0.62) | KMT2AMEN1KDM4EMAPTCYP19A1 | |
| SCHEMBL15364313 | 0.92 | KMT2A (0.62) | KMT2AMEN1KDM4EMAPTCYP19A1 | |
| SCHEMBL3229347 | 0.92 | KMT2A (0.62) | KMT2AMEN1KDM4EMAPTCYP19A1 | |
| SCHEMBL15364341 | 0.92 | KMT2A (0.62) | KMT2AMEN1KDM4EMAPTCYP19A1 | |
| SCHEMBL15364345 | 0.92 | KMT2A (0.62) | KMT2AMEN1KDM4EMAPTCYP19A1 | |
| SCHEMBL30775463 | 0.92 | KMT2A (0.62) | KMT2AMEN1KDM4EMAPTCYP19A1 | |
| SCHEMBL28545557 | 0.85 | CA12 (0.57) | KMT2AMEN1HSD11B1KDM4EGAA | |
| SCHEMBL16024193 | 0.84 | KMT2A (0.55) | KMT2AMEN1KDM4EGAAMAPT | |
| SCHEMBL21515007 | 0.84 | CYP19A1 (0.65) | KMT2AMEN1KDM4EMAPTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101402611-A | Compound with anti-leukocythemia liveness and method of preparing the same | UNIV GUANGDONG PHARM (CN) | 2009-04-08 | — | — | CN | disclosed |