Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.45 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935690 | 0.76 | ESR1 (0.42) | ESR1CES2CES1PTGS2CYP19A1 | |
| SCHEMBL377450 | 0.76 | ESR1 (0.42) | ESR1CES2CES1PTGS2CYP19A1 | |
| SCHEMBL15364809 | 0.75 | PTGS2 (0.42) | ESR1CES2CES1PTGS2CYP19A1 | |
| SCHEMBL12294540 | 0.75 | ESR1 (0.41) | ESR1CES2CES1PTGS2CYP19A1 | |
| SCHEMBL15364416 | 0.73 | ESR1 (0.39) | ESR1CES2CES1PTGS2CYP19A1 | |
| SCHEMBL5988427 | 0.73 | ESR1 (0.52) | ESR1CES2CES1PTGS2CYP19A1 | |
| SCHEMBL28481713 | 0.73 | ESR1 (0.58) | ESR1CES2CES1PTGS2CYP19A1 | |
| Methyl Alcohol SCHEMBL28843164 | 0.72 | ESR1 (0.50) | ESR1CES2CES1PTGS2CYP19A1 | |
| SCHEMBL15364428 | 0.72 | PTGS2 (0.44) | ESR1CES2CES1PTGS2CYP19A1 | |
| SCHEMBL67982 | 0.71 | CES1 (0.53) | ESR1CES2CES1PTGS2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9868805-B2 | Polydienes and diene copolymers having organophosphine functionality | BRIDGESTONE CORPORATION (JP) | 2018-01-16 | — | — | US | disclosed |
| EP-2844678-B1 | POLYDIENES AND DIENE COPOLYMERS HAVING ORGANOPHOSPHINE FUNCTIONALITY | BRIDGESTONE CORP (JP) | 2017-02-22 | — | — | EP | disclosed |
| US-9499651-B2 | Copolymers of conjugated dienes and vinyl organophosphines prepared by anionic polymerization | BRIDGESTONE CORPORATION (JP) | 2016-11-22 | — | — | US | disclosed |
| US-9127109-B2 | Preparation of functional polymers phosphorus-containing organometal initiators | BRIDGESTONE CORPORATION (JP) | 2015-09-08 | — | — | US | disclosed |
| US-20150126675-A1 | Polydienes And Diene Copolymers Having Organophosphine Functionality | BRIDGESTONE CORPORATION (JO) | 2015-05-07 | — | — | US | disclosed |
| EP-2844678-A1 | POLYDIENES AND DIENE COPOLYMERS HAVING ORGANOPHOSPHINE FUNCTIONALITY | Bridgestone Corporation (JP) | 2015-03-11 | — | — | EP | disclosed |
| US-20140275428-A1 | Copolymers Of Conjugated Dienes And Vinyl Organophosphines Prepared By Anionic Polymerization | BRIDGESTONE CORPORATION (JP) | 2014-09-18 | — | — | US | disclosed |
| US-20130296480-A1 | PREPARATION OF FUNCTIONAL POLYMERS PHOSPHORUS-CONTAINING ORGANOMETAL INITIATORS | BRIDGESTONE CORPORATION (JP) | 2013-11-07 | — | — | US | disclosed |
| WO-2013166124-A1 | POLYDIENES AND DIENE COPOLYMERS HAVING ORGANOPHOSPHINE FUNCTIONALITY | BRIDGESTONE CORPORATION (JP) | 2013-11-07 | — | — | WO | disclosed |