Sugi Predict

Sugi Predict / Compounds / SCHEMBL377450

SCHEMBL377450

SCHEMBL377450

CC(=C(c1ccccc1)c1ccccc1)P(C(C)(C)C)C(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 3/20 0.42
▸ CES2 O00748 2/20 0.38
▸ CES1 P23141 2/20 0.38
▸ PTGS2 P35354 4/20 0.36
▸ ALDH1A1 P00352 2/20 0.35
▸ TSHR P16473 2/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ CYP19A1 P11511 3/20 0.34
▸ ESR2 Q92731 1/20 0.34
▸ GAA P10253 1/20 0.34
▸ DAO P14920 1/20 0.33
▸ NAPRT Q6XQN6 1/20 0.33
▸ POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6935597 0.78 ALDH1A1 (0.44) ALDH1A1TSHRHSD17B10GAAPOLB
SCHEMBL15364413 0.76 ESR1 (0.45) ESR1CES2CES1PTGS2ALDH1A1
SCHEMBL6935690 0.73 ESR1 (0.42) ESR1CES2CES1PTGS2TSHR
SCHEMBL15364809 0.71 PTGS2 (0.42) ESR1CES2CES1PTGS2HSD17B10
SCHEMBL12294540 0.71 ESR1 (0.41) ESR1CES2CES1PTGS2ALDH1A1
SCHEMBL20955860 0.70 CES1 (0.46) CES2CES1ALDH1A1TSHRHSD17B10
SCHEMBL18159828 0.70 PTGS2 (0.38) ESR1CES2CES1PTGS2ALDH1A1
SCHEMBL15364416 0.70 ESR1 (0.39) ESR1CES2CES1PTGS2ALDH1A1
SCHEMBL5988427 0.69 ESR1 (0.52) ESR1CES2CES1PTGS2ALDH1A1
SCHEMBL28481713 0.69 ESR1 (0.58) ESR1CES2CES1PTGS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116368134-A Methods of making ubiquitin JAK inhibitors and related intermediate compounds 施万生物制药研发IP有限责任公司 2023-06-30 — — CN claimed
CN-112094165-A Method for preparing biaryl compound by Suzuki coupling reaction 浙江省化工研究院有限公司 2020-12-18 — — CN claimed
US-9233922-B2 Process for producing N-(hetero)arylazoles TAKASAGO INTERNATIONAL CORPORATION (JP) 2016-01-12 — — US claimed
US-20260138995-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-05-21 — — US disclosed
EP-4723858-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2026-04-08 — — EP disclosed
US-12545690-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-02-10 — — US disclosed
EP-4059915-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2025-12-24 — — EP disclosed
EP-4646413-A1 SOLID FORMS OF A CDK2 INHIBITOR Blueprint Medicines Corporation (US) 2025-11-12 — — EP disclosed
US-20250230353-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-07-17 — — US disclosed
US-20240400485-A1 PROCESS FOR THE HYDROFORMYLATION OF PROPYLENE UNIVERSITÉ DE STRASBOURG (FR) 2024-12-05 — — US disclosed
WO-2024148083-A1 SOLID FORMS OF A CDK2 INHIBITOR BLUEPRINT MEDICINES CORPORATION (US) 2024-07-11 — — WO disclosed
EP-2410380-B1 Electrophotographic photoreceptor TAKASAGO PERFUMERY CO LTD (JP) 2013-10-02 — — EP disclosed
WO-2013032035-A1 PROCESS FOR PRODUCING N-(HETERO)ARYLAZOLES TAKASAGO INTERNATIONAL CORPORATION (JP) 2013-03-07 — — WO disclosed
WO-2013032035-A1 PROCESS FOR PRODUCING N-(HETERO)ARYLAZOLES TAKASAGO INTERNATIONAL CORPORATION (JP) 2013-03-07 — — WO disclosed
US-20120022293-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR TAKASAGO INTERNATIONAL CORPORATION (JP) 2012-01-26 — — US disclosed
EP-2410380-A2 Electrophotographic photoreceptor Takasago International Corporation (JP) 2012-01-25 — — EP disclosed
EP-1167372-B1 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst TAKASAGO PERFUMERY CO LTD (JP) 2003-12-10 — — EP disclosed
US-6455720-B1 AS CATALYSTS TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-09-24 — — US disclosed
US-20020058837-A1 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-05-16 — — US disclosed
EP-1167372-A1 2,2-(Diaryl)vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst Takasago International Corporation (JP) 2002-01-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020058837-A1 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst DDT, PDCD11, PLD2 ESR1 3506/4885CES2 3946/4885CES1 3736/4885
US-12545690-B2 Organic electroluminescent materials and devices LBR, OPRD1, NR1H2 ESR1 166/4885CES2 1838/4885CES1 2326/4885
US-20120022293-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR SLC1A2, SLC18A2, SLC1A1 ESR1 2122/4885CES2 2886/4885CES1 4294/4885
US-20260138995-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NR1H2, NR1H3, XDH ESR1 504/4885CES2 1977/4885CES1 2770/4885
US-20250230353-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OSBP ESR1 42/4885CES2 577/4885CES1 2037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.