Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15366642 | 1.00 | KMT2A (0.38) | KMT2AL3MBTL1GAA | |
| SCHEMBL15366637 | 1.00 | KMT2A (0.38) | KMT2AL3MBTL1GAA | |
| SCHEMBL15366461 | 0.93 | KMT2A (0.37) | KMT2AL3MBTL1GAA | |
| SCHEMBL15366462 | 0.93 | KMT2A (0.37) | KMT2AL3MBTL1GAA | |
| SCHEMBL15366459 | 0.93 | KMT2A (0.37) | KMT2AL3MBTL1GAA | |
| SCHEMBL15370881 | 0.93 | NAAA (0.37) | KMT2AL3MBTL1 | |
| SCHEMBL15370890 | 0.92 | KMT2A (0.36) | KMT2AL3MBTL1GAA | |
| SCHEMBL18315409 | 0.86 | KMT2A (0.36) | KMT2AL3MBTL1GAA | |
| SCHEMBL18315410 | 0.86 | KMT2A (0.36) | KMT2AL3MBTL1GAA | |
| SCHEMBL15371020 | 0.85 | ABCB1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2847188-B1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-12-21 | — | — | EP | disclosed |
| US-8835462-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES, LLC. (US) | 2014-09-16 | — | — | US | disclosed |
| US-20130296373-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2013-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130296373-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | CYP4F12, CYP1A2, FKBP14 | KMT2A 3561/4885L3MBTL1 4150/4885GAA 1613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.