SCHEMBL15372784

SCHEMBL15372784

OOCC1c2ccccc2-c2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
HTR2A P28223 2/20 0.52
KMT2A Q03164 2/20 0.46
FABP5 Q01469 3/20 0.45
FABP7 O15540 2/20 0.45
EPHX2 P34913 1/20 0.43
POLB P06746 1/20 0.39
TDO2 P48775 1/20 0.39
GPR3 P46089 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2730698 0.81 CA1 (0.57) CA1CA2HTR2AKMT2AFABP5
SCHEMBL2782675 0.79 KMT2A (0.56) CA1CA2HTR2AKMT2AFABP5
SCHEMBL30667581 0.79 KMT2A (0.56) CA1CA2HTR2AKMT2AFABP5
SCHEMBL15436860 0.78 CA1 (0.50) CA1CA2HTR2AKMT2AFABP5
SCHEMBL31370732 0.77 HTR2A (0.58) CA1CA2HTR2AKMT2AFABP5
SCHEMBL456018 0.77 CA1 (0.53) CA1CA2HTR2AKMT2AFABP5
SCHEMBL20362789 0.77 CA1 (0.53) CA1CA2HTR2AKMT2AFABP5
SCHEMBL4992955 0.77 CA1 (0.53) CA1CA2HTR2AKMT2AFABP5
SCHEMBL8131 0.77 CA1 (0.58) CA1CA2HTR2AKMT2AFABP5
SCHEMBL28050 0.77 HTR2A (0.58) CA1CA2HTR2AKMT2AFABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022269251-A1 ACRYLAMIDE DERIVATIVES USEFUL AS ANTI-INFLAMMATORY AGENTS SITRYX THERAPEUTICS LIMITED (GB) 2022-12-29 WO disclosed
EP-3768729-B1 CONJUGATES OF STANOZOLOL AND HYALURONIC ACID ACME DRUGS S R L (IT) 2022-01-26 EP disclosed
EP-2256349-B1 MICRO FLUID DEVICE SEKISUI CHEMICAL CO LTD (JP) 2017-04-26 EP disclosed
EP-3130608-A1 (ANTI-HER2 ANTIBODY)-DRUG CONJUGATE Daiichi Sankyo Co., Ltd. (JP) 2017-02-15 EP disclosed
EP-3088419-A1 ANTI-TROP2 ANTIBODY-DRUG CONJUGATE DAIICHI SANKYO COMPANY, LIMITED (JP) 2016-11-02 EP disclosed
WO-2016120456-A1 SUPRAMOLECULAR POLYMER BLEND TECHNISCHE UNIVERSITEIT EINDHOVEN (NL) 2016-08-04 WO disclosed
WO-2016077518-A1 MACROCYCLIC PEPTIDES USEFUL AS IMMUNOMODULATORS BRISTOL-MYERS SQUIBB COMPANY (US) 2016-05-19 WO disclosed
WO-2016019340-A1 POLYOXAZOLINE ANTIBODY DRUG CONJUGATES SERINA THERAPEUTICS, INC. (US) 2016-02-04 WO disclosed
WO-2015155976-A1 (ANTI-HER2 ANTIBODY)-DRUG CONJUGATE 第一三共株式会社 2015-10-15 WO disclosed
WO-2015146132-A1 ANTI-CD98 ANTIBODY-DRUG CONJUGATE 第一三共株式会社 2015-10-01 WO disclosed
EP-2910573-A1 ANTIBODY-DRUG CONJUGATE PRODUCED BY BINDING THROUGH LINKER HAVING HYDROPHILIC STRUCTURE DAIICHI SANKYO COMPANY, LIMITED (JP) 2015-08-26 EP disclosed
EP-2907824-A1 ANTIBODY-DRUG CONJUGATE DAIICHI SANKYO COMPANY, LIMITED (JP) 2015-08-19 EP disclosed
WO-2015098099-A1 ANTI-TROP2 ANTIBODY-DRUG CONJUGATE 第一三共株式会社 2015-07-02 WO disclosed
WO-2015081282-A1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE REDWOOD BIOSCIENCE, INC. (US) 2015-06-04 WO disclosed
WO-2014057687-A1 ANTIBODY-DRUG CONJUGATE 第一三共株式会社 (JP) 2014-04-17 WO disclosed
EP-2257534-B1 3-AMINOALKYL-1,4-DIAZEPAN-2-ONE MELANOCORTIN-5 RECEPTOR ANTAGONISTS MIMETICA PTY LTD (AU) 2013-11-06 EP disclosed
US-20130052130-A1 Branched Discreet PEG Constructs UNIVERSITY OF WASHINGTON (US) 2013-02-28 US disclosed
EP-2258951-A1 PHOTORESPONSIVE GAS-GENERATING MATERIAL, MICROPUMP AND MICROFLUID DEVICE Sekisui Chemical Co., Ltd. (JP) 2010-12-08 EP disclosed
EP-2256349-A1 MICRO FLUID DEVICE Sekisui Chemical Co., Ltd. (JP) 2010-12-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130052130-A1 Branched Discreet PEG Constructs BTD, DNPEP, IDUA CA1 1384/4885CA2 3649/4885HTR2A 4806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.