SCHEMBL8131

SCHEMBL8131

NOCC1c2ccccc2-c2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
HTR2A P28223 2/20 0.58
KMT2A Q03164 2/20 0.46
FABP5 Q01469 3/20 0.41
FABP7 O15540 2/20 0.41
EPHX2 P34913 1/20 0.40
GPR3 P46089 1/20 0.37
POLB P06746 1/20 0.35
TDO2 P48775 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2730698 0.81 CA1 (0.57) CA1CA2HTR2AKMT2AFABP5
SCHEMBL456018 0.77 CA1 (0.53) CA1CA2HTR2AKMT2AFABP5
SCHEMBL20362789 0.77 CA1 (0.53) CA1CA2HTR2AKMT2AFABP5
SCHEMBL15372784 0.77 CA1 (0.53) CA1CA2HTR2AKMT2AFABP5
SCHEMBL31501939 0.77 CA1 (0.53) CA1CA2HTR2AKMT2AFABP5
SCHEMBL4992955 0.77 CA1 (0.53) CA1CA2HTR2AKMT2AFABP5
SCHEMBL31370732 0.77 HTR2A (0.58) CA1CA2HTR2AKMT2AFABP5
SCHEMBL28050 0.77 HTR2A (0.58) CA1CA2HTR2AKMT2AFABP5
SCHEMBL158137 0.77 CA1 (0.53) CA1CA2HTR2AKMT2AFABP5
SCHEMBL17167370 0.75 KMT2A (0.56) CA1CA2HTR2AKMT2AFABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1417 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4678680-A1 METHOD FOR PRODUCING POLYALKYLENE OXIDE-MODIFIED PHOSPHOLIPID NOF Corporation (JP) 2026-01-14 EP claimed
WO-2024185762-A1 METHOD FOR PRODUCING POLYALKYLENE OXIDE-MODIFIED PHOSPHOLIPID 日油株式会社 2024-09-12 WO claimed
US-12611461-B2 Bioorthogonal compositions TAMBO, INC. (US) 2026-04-28 US disclosed
US-12611462-B2 Compounds and compositions including phosphorothioated oligodeoxynucleotide, and methods of use thereof CITY OF HOPE (US) 2026-04-28 US disclosed
US-12589162-B2 Trans-cyclooctene prodrug of monomethyl auristatin E TAMBO, INC. (US) 2026-03-31 US disclosed
US-12570621-B2 Short-acting 3,4-methylenedioxymethamphetamine (MDMA) analogs incorporating benzothiazole APOAPSIS HOLDINGS, LLC (US) 2026-03-10 US disclosed
US-12569466-B2 Short-acting psychoactive compounds of the MDMA class APOAPSIS HOLDINGS, LLC (US) 2026-03-10 US disclosed
US-20260028662-A1 OPLOPHORUS-DERIVED LUCIFERASES, NOVEL COELENTERAZINE SUBSTRATES, AND METHODS OF USE PROMEGA CORP (US) 2026-01-29 US disclosed
US-12527874-B2 Bioorthogonal compositions TAMBO, INC. (US) 2026-01-20 US disclosed
EP-4678680-A1 METHOD FOR PRODUCING POLYALKYLENE OXIDE-MODIFIED PHOSPHOLIPID NOF Corporation (JP) 2026-01-14 EP disclosed
US-20260007759-A1 TRANS-CYCLOOCTENE PRODRUG OF MONOMETHYL AURISTATIN E TAMBO, INC. 2026-01-08 US disclosed
US-20020183325-A1 Therapy of disease of the human or animal body mediated by poly ADP-ribosyltransferase (PARP) by administering phthalazinone derivatives KUDOS PHARMACEUTICALS LIMITED (GB) 2002-12-05 US disclosed
WO-2002090334-A1 ISOQUINOLINONE DERIVATIVES AS PARP INHIBITORS KUDOS PHARMACEUTICALS LIMITED (GB) 2002-11-14 WO disclosed
WO-2002036576-A1 PHTHALAZINONE DERIVATIVES KUDOS PHARMACEUTICALS LIMITED (GB) 2002-05-10 WO disclosed
WO-2002030879-A2 CARBAMIC ACID COMPOUNDS COMPRISING A SULFONAMIDE LINKAGE AS HDAC INHIBITORS PROLIFIX LIMITED (GB) 2002-04-18 WO disclosed
WO-2002030932-A2 N8,N13-DISUBSTITUTED QUINO[4,3,2-KL]ACRIDINIUM SALTS AS THERAPEUTIC AGENTS CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2002-04-18 WO disclosed
WO-2002026696-A1 CARBAMIC ACID COMPOUNDS COMPRISING AN AMIDE LINKAGE AS HDAC INHIBITORS PROLIFIX LIMITED (GB) 2002-04-04 WO disclosed
WO-2002026703-A1 CARBAMIC ACID COMPOUNDS COMPRISING AN ETHER LINKAGE AS HDAC INHIBITORS PROLIFIX LIMITED (GB) 2002-04-04 WO disclosed
WO-2002008193-A2 THERAPEUTIC ACRIDONE AND ACRIDINE COMPOUNDS CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2002-01-31 WO disclosed
WO-2001093841-A2 BARBITURIC ACID ANALOGS AS THERAPEUTIC AGENTS NOVUSPHARMA S.P.A. (IT) 2001-12-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570621-B2 Short-acting 3,4-methylenedioxymethamphetamine (MDMA) analogs incorporating benzothiazole SLC6A3, SLC6A2, HTR2C CA1 4822/4885CA2 4755/4885HTR2A 31/4885
US-20020183325-A1 Therapy of disease of the human or animal body mediated by poly ADP-ribosyltransferase (PARP) by administering phthalazinone derivatives PARP1, PARP11, PARP3 CA1 1684/4885CA2 2855/4885HTR2A 1651/4885
US-12589162-B2 Trans-cyclooctene prodrug of monomethyl auristatin E AURKC, AURKA, QPCT CA1 148/4885CA2 582/4885HTR2A 4536/4885
US-12611462-B2 Compounds and compositions including phosphorothioated oligodeoxynucleotide, and methods of use thereof STAT3, NSUN2, STAT1 CA1 2612/4885CA2 3575/4885HTR2A 4050/4885
US-20260028662-A1 OPLOPHORUS-DERIVED LUCIFERASES, NOVEL COELENTERAZINE SUBSTRATES, AND METHODS OF USE RNGTT, VIP, PREP CA1 3819/4885CA2 3928/4885HTR2A 3557/4885
US-12611461-B2 Bioorthogonal compositions ACVRL1, FCGR2A, CHIT1 CA1 169/4885CA2 447/4885HTR2A 4159/4885
US-20260007759-A1 TRANS-CYCLOOCTENE PRODRUG OF MONOMETHYL AURISTATIN E CCL5, CXCL10, SLC7A11 CA1 203/4885CA2 887/4885HTR2A 4553/4885
US-12569466-B2 Short-acting psychoactive compounds of the MDMA class HTR2C, SLC6A2, DRD2 CA1 4795/4885CA2 4605/4885HTR2A 11/4885
US-12527874-B2 Bioorthogonal compositions CD44, FLNA, H1-5 CA1 1888/4885CA2 3888/4885HTR2A 157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.