SCHEMBL9426164

SCHEMBL9426164

C[Si](C)(C)[Si](C)(c1ccc(N)cc1)c1ccc(N)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
ACHE P22303 2/20 0.41
ALDH1A1 P00352 10/20 0.38
TDP1 Q9NUW8 8/20 0.38
CYP3A4 P08684 7/20 0.38
TP53 P04637 3/20 0.38
NPC1 O15118 3/20 0.37
RAB9A P51151 3/20 0.37
KDM4E B2RXH2 2/20 0.37
MAPK1 P28482 5/20 0.36
ALOX15 P16050 3/20 0.36
TSHR P16473 4/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
HSD17B10 Q99714 2/20 0.35
LMNA P02545 1/20 0.35
CYP2D6 P10635 1/20 0.35
CHRM1 P11229 1/20 0.35
KCNA1 Q09470 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3923695 0.77 MEN1 (0.50) MAPTMEN1KMT2AACHEALDH1A1
SCHEMBL22694323 0.77 MEN1 (0.50) MAPTMEN1KMT2AACHEALDH1A1
SCHEMBL1172568 0.77 MEN1 (0.50) MAPTMEN1KMT2AACHEALDH1A1
SCHEMBL65963 0.77 MEN1 (0.50) MAPTMEN1KMT2AACHEALDH1A1
Ethane SCHEMBL3211361 0.74 MEN1 (0.47) MAPTMEN1KMT2AACHEALDH1A1
SCHEMBL9326306 0.72 MEN1 (0.44) MAPTMEN1KMT2AACHEALDH1A1
SCHEMBL4516363 0.72 MEN1 (0.44) MAPTMEN1KMT2AACHEALDH1A1
SCHEMBL10617640 0.72 CYP2A6 (0.44) ALDH1A1TDP1NPC1RAB9AKDM4E
SCHEMBL124891 0.72 MAPT (0.38) MAPTMEN1KMT2AACHEALDH1A1
SCHEMBL242201 0.71 ESR1 (0.44) MAPTACHEALDH1A1TP53NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6264267-A None JP disclosed
EP-2662378-B1 IMIDE COMPOUND, METHOD FOR PRODUCING SAME, THICKENING AGENT FOR GREASE, AND GREASE COMPOSITION JX NIPPON OIL & ENERGY CORP (JP) 2018-10-10 EP disclosed
US-9487726-B2 Imide compound, method for producing same, thickening agent for grease, and grease composition JX NIPPON OIL & ENERGY CORPORATION (JP) 2016-11-08 US disclosed
US-20130345102-A1 IMIDE COMPOUND, METHOD FOR PRODUCING SAME, THICKENING AGENT FOR GREASE, AND GREASE COMPOSITION JX NIPPON OIL & ENERGY CORPORATION (JP) 2013-12-26 US disclosed
EP-2662378-A1 IMIDE COMPOUND, METHOD FOR PRODUCING SAME, THICKENING AGENT FOR GREASE, AND GREASE COMPOSITION JX Nippon Oil & Energy Corporation (JP) 2013-11-13 EP disclosed
JP-H06264267-A PATTERN FORMING METHOD HITACHI LTD 1994-09-20 JP disclosed