Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.54 |
| ▸ | TOP1 | P11387 | 1/20 | 0.42 |
| ▸ | CYCS | P99999 | 3/20 | 0.41 |
| ▸ | TERT | O14746 | 4/20 | 0.39 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1613981 | 0.98 | ENPP2 (0.55) | ENPP2TOP1CYCSTERTPGAM1 | |
| SCHEMBL30925048 | 0.97 | ENPP2 (0.54) | ENPP2TOP1CYCSTERTPGAM1 | |
| SCHEMBL1537566 | 0.97 | ENPP2 (0.57) | ENPP2TOP1CYCSTERT | |
| SCHEMBL8506340 | 0.92 | ENPP2 (0.59) | ENPP2TOP1CYCSTERT | |
| SCHEMBL6513613 | 0.85 | ENPP2 (0.50) | ENPP2TOP1CYCSTERT | |
| SCHEMBL9290728 | 0.82 | ENPP2 (0.47) | ENPP2TOP1CYCSTERTPGAM1 | |
| SCHEMBL1537557 | 0.82 | ENPP2 (0.47) | ENPP2TOP1CYCSTERTPGAM1 | |
| SCHEMBL5178493 | 0.82 | ENPP2 (0.47) | ENPP2TOP1CYCSTERTPGAM1 | |
| SCHEMBL4389090 | 0.81 | STAT3 (0.52) | ENPP2TOP1CYCSPGAM1 | |
| SCHEMBL8351335 | 0.77 | ENPP2 (0.51) | ENPP2TOP1CYCSTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110064694-A1 | ANTI-HEPATITIS C ACTIVITY OF MESO-TETRAKIS-PORPHYRIN ANALOGUES | YALE UNIVERSITY (US) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110064694-A1 | ANTI-HEPATITIS C ACTIVITY OF MESO-TETRAKIS-PORPHYRIN ANALOGUES | HAVCR2, HCCS, HMBS | ENPP2 1541/4885TOP1 2148/4885CYCS 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.