SCHEMBL15375604

SCHEMBL15375604

CNC(=O)C(OC)c1ccc(Cl)cc1COc1ccccc1C

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 1/20 0.47
CYP1A2 P05177 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
CYP2C19 P33261 1/20 0.44
SGMS2 Q8NHU3 3/20 0.43
ANO1 Q5XXA6 2/20 0.43
FABP4 P15090 1/20 0.42
FABP5 Q01469 1/20 0.42
ANO2 Q9NQ90 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
PTGER1 P34995 2/20 0.41
ALDH1A1 P00352 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
RECQL P46063 1/20 0.40
MRGPRX4 Q96LA9 1/20 0.40
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15375456 0.91 PTGDR2 (0.47) PTGDR2CYP1A2MEN1KMT2ACYP2C19
SCHEMBL17328310 0.89 FABP4 (0.44) PTGDR2MEN1KMT2ASGMS2FABP4
SCHEMBL15375473 0.88 PTGDR2 (0.43) PTGDR2MEN1KMT2ASGMS2SMN1; SMN2
SCHEMBL15375472 0.88 FABP4 (0.43) PTGDR2SGMS2FABP4FABP5L3MBTL1
SCHEMBL15375648 0.87 PTGDR2 (0.48) PTGDR2CYP1A2MEN1KMT2ACYP2C19
SCHEMBL2236821 0.86 FABP4 (0.46) CYP1A2SGMS2FABP4FABP5L3MBTL1
SCHEMBL15402503 0.81 PTGDR2 (0.49) PTGDR2CYP1A2MEN1KMT2ACYP2C19
SCHEMBL15375584 0.81 POLB (0.40) MEN1KMT2AL3MBTL1PTGER1ALDH1A1
SCHEMBL15375580 0.81 BCHE (0.39) FABP4FABP5L3MBTL1PTGER1ALDH1A1
SCHEMBL15375526 0.80 PTGDR2 (0.48) PTGDR2CYP1A2MEN1KMT2ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2682382-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-23 EP disclosed
EP-2662352-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-09 EP disclosed
CN-103588657-B The manufacture method of phenylacetyl amines 住友化学株式会社 2016-06-22 CN disclosed
EP-2397459-B1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-12-16 EP disclosed
CN-103641731-B The manufacture method of phenylacetyl amine compound SUMITOMO CHEMICAL CO., LTD. (JP) 2015-10-28 CN disclosed
EP-2682382-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2014-01-08 EP disclosed
US-8624062-B2 Method for producing phenylacetamide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-07 US disclosed
EP-2662352-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2013-11-13 EP disclosed
EP-2397459-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-12-21 EP disclosed
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND MRPL21, AADAC, ARSA PTGDR2 938/4885CYP1A2 126/4885MEN1 4702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.