SCHEMBL15375472

SCHEMBL15375472

CNC(=O)C(OC)c1ccc(Cl)cc1COc1ccccc1C(C)C

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 1/20 0.43
FABP5 Q01469 1/20 0.43
LPAR1 Q92633 4/20 0.43
SGMS2 Q8NHU3 5/20 0.40
ALDH1A1 P00352 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HTR1A P08908 1/20 0.39
HTR7 P34969 1/20 0.39
PTGER1 P34995 3/20 0.39
PTGDR2 Q9Y5Y4 1/20 0.39
MRGPRX4 Q96LA9 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15375580 0.88 BCHE (0.39) FABP4FABP5LPAR1ALDH1A1NPSR1
SCHEMBL17328310 0.88 FABP4 (0.44) FABP4FABP5SGMS2ALDH1A1NPSR1
SCHEMBL15375604 0.88 PTGDR2 (0.47) FABP4FABP5SGMS2ALDH1A1NPSR1
SCHEMBL15402402 0.88 FABP4 (0.46) FABP4FABP5LPAR1ALDH1A1L3MBTL1
SCHEMBL15375528 0.87 LPAR1 (0.42) FABP4FABP5LPAR1SGMS2HTR1A
SCHEMBL14906285 0.82 LPAR1 (0.47) LPAR1ALDH1A1L3MBTL1
SCHEMBL15401610 0.82 BCHE (0.40) FABP4FABP5LPAR1
SCHEMBL15401433 0.81 LPAR1 (0.45) FABP4FABP5LPAR1SGMS2HTR1A
SCHEMBL15375473 0.81 PTGDR2 (0.43) SGMS2ALDH1A1NPSR1PTGDR2MRGPRX4
SCHEMBL15375584 0.80 POLB (0.40) ALDH1A1NPSR1L3MBTL1PTGER1MRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2682382-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-23 EP disclosed
EP-2662352-B1 Method for Producing Phenylacetamide Compound SUMITOMO CHEMICAL CO (JP) 2016-11-09 EP disclosed
EP-2397459-B1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-12-16 EP disclosed
EP-2682382-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2014-01-08 EP disclosed
US-8624062-B2 Method for producing phenylacetamide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-07 US disclosed
EP-2662352-A2 Method for Producing Phenylacetamide Compound Sumitomo Chemical Company, Limited (JP) 2013-11-13 EP disclosed
EP-2397459-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-12-21 EP disclosed
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295035-A1 METHOD FOR PRODUCING PHENYLACETAMIDE COMPOUND MRPL21, AADAC, ARSA FABP4 4349/4885FABP5 4435/4885LPAR1 3283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.