SCHEMBL1537561

SCHEMBL1537561

O=C[C@H](OC(=O)O)[C@@H](O)[C@H](O)[C@H](O)CO.[CaH2]

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.44
LMNA P02545 2/20 0.41
USP2 O75604 1/20 0.41
SLCO1B1 Q9Y6L6 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TDP1 Q9NUW8 1/20 0.39
AKR1B1 P15121 1/20 0.32
KDM4E B2RXH2 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10738624 0.98 PDE4A (0.45) PDE4ALMNAUSP2SLCO1B1L3MBTL1
SCHEMBL419462 0.98 PDE4A (0.45) PDE4ALMNAUSP2SLCO1B1L3MBTL1
SCHEMBL17144674 0.98 PDE4A (0.45) PDE4ALMNAUSP2SLCO1B1L3MBTL1
SCHEMBL10743488 0.96 TDP1 (0.44) PDE4ALMNAUSP2SLCO1B1L3MBTL1
SCHEMBL18730385 0.96 PDE4A (0.44) PDE4ALMNAUSP2SLCO1B1L3MBTL1
SCHEMBL1129405 0.92 PDE4A (0.42) PDE4ALMNAUSP2SLCO1B1L3MBTL1
SCHEMBL1607591 0.92 PDE4A (0.42) PDE4ALMNAUSP2SLCO1B1L3MBTL1
SCHEMBL2122285 0.91 PDE4A (0.41) PDE4ALMNAUSP2SLCO1B1L3MBTL1
SCHEMBL11232979 0.84 PDE4A (0.42) PDE4ALMNAUSP2SLCO1B1L3MBTL1
SCHEMBL8384985 0.84 PDE4A (0.38) PDE4ALMNAUSP2SLCO1B1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005118488-A1 IDENTIFICATION OF CALCIUM CARBONATE DISSOLVING BACTERIA AND ITS POSSIBLE INDUSTRIAL UTILIZATION YEDITEPE UNIVERSITY (TR) 2005-12-15 WO claimed
US-10081832-B2 Hyperprimers EZYGENE PTY LTD. (AU) 2018-09-25 US disclosed
EP-2510125-B1 HYPERPRIMERS EZYGENE PTY LTD (AU) 2018-08-22 EP disclosed
US-20120295251-A1 DETERMINING CODON DISTRIBUTION AND/OR BASE PAIR DISTANCE BETWEEN CODONS IN A NUCLEIC ACID EZYGENE PTY LTD. (AU) 2012-11-22 US disclosed
EP-2510125-A1 HYPERPRIMERS Ezygene Pty Ltd (AU) 2012-10-17 EP disclosed
US-8227186-B1 Methods and compositions relating to bioluminescent microorganisms THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2012-07-24 US disclosed
WO-2011069200-A1 HYPERPRIMERS EZYGENE PTY LTD (AU) 2011-06-16 WO disclosed
US-7914811-B2 Weight ratio of active drug agents with particle size >/= 50 mu m to shell being 1:5-1:15 MCNEIL-PPC, INC. (US) 2011-03-29 US disclosed
EP-2065025-A2 A preservative composition and its use, a method of preparing it and formulations containing it Capelli, Cristina (IT) 2009-06-03 EP disclosed
WO-2005118488-A1 IDENTIFICATION OF CALCIUM CARBONATE DISSOLVING BACTERIA AND ITS POSSIBLE INDUSTRIAL UTILIZATION YEDITEPE UNIVERSITY (TR) 2005-12-15 WO disclosed
US-20030017202-A1 Brittle-coating, soft core dosage form CHENANGO ZERO LLC 2003-01-23 US disclosed
EP-1273291-A1 Brittle-coating, soft core dosage form McNEIL-PPC, INC. (US) 2003-01-08 EP disclosed
US-4900348-A Production of disease suppresive compost and container media, and microorganism culture for use therein THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1990-02-13 US disclosed