Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10738624 | 1.00 | PDE4A (0.45) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL17144674 | 1.00 | PDE4A (0.45) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL18730385 | 0.98 | PDE4A (0.44) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL10743488 | 0.98 | TDP1 (0.44) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL1537561 | 0.98 | PDE4A (0.44) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL1607591 | 0.94 | PDE4A (0.42) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL1129405 | 0.94 | PDE4A (0.42) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL2122285 | 0.92 | PDE4A (0.41) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL11232979 | 0.85 | PDE4A (0.42) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL8384985 | 0.85 | PDE4A (0.38) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3432894-A1 | A PHARMACEUTICAL OR VETERINARY COMPOSITION | Epsilion Limited (IE) | 2019-01-30 | — | — | EP | claimed |
| WO-2017162702-A1 | A PHARMACEUTICAL OR VETERINARY COMPOSITION | EPSILION LIMITED (IE) | 2017-09-28 | — | — | WO | claimed |
| US-11931497-B2 | System and method for preparing peritoneal dialysis fluid at the time of use | BAXTER INTERNATIONAL INC. (US) | 2024-03-19 | — | — | US | disclosed |
| US-20220211926-A1 | SYSTEM AND METHOD FOR PREPARING PERITONEAL DIALYSIS FLUID AT THE TIME OF USE | VANTIVE US HEALTHCARE LLC | 2022-07-07 | — | — | US | disclosed |
| US-11311657-B2 | Dialysis system for mixing treatment fluid at time of use | BAXTER INTERNATIONAL INC. (US) | 2022-04-26 | — | — | US | disclosed |
| US-20190298906-A1 | DIALYSIS SYSTEM FOR MIXING TREATMENT FLUID AT TIME OF USE | VANTIVE US HEALTHCARE LLC | 2019-10-03 | — | — | US | disclosed |
| US-10335532-B2 | Dialysis system having autoidentification mechanism | BAXTER INTERNATIONAL INC. (US) | 2019-07-02 | — | — | US | disclosed |
| EP-3432894-A1 | A PHARMACEUTICAL OR VETERINARY COMPOSITION | Epsilion Limited (IE) | 2019-01-30 | — | — | EP | disclosed |
| WO-2017162702-A1 | A PHARMACEUTICAL OR VETERINARY COMPOSITION | EPSILION LIMITED (IE) | 2017-09-28 | — | — | WO | disclosed |
| US-8920362-B2 | Dialysis system having disposable cassette | BAXTER INTERNATIONAL INC. (US) | 2014-12-30 | — | — | US | disclosed |
| US-8764702-B2 | Dialysis system having dual patient line connection and prime | BAXTER INTERNATIONAL INC. (US) | 2014-07-01 | — | — | US | disclosed |
| US-5420107-A | Fluids, inorganic lactic acid salts and administering | BROOKS, GEORGE A. | 1995-05-30 | — | — | US | disclosed |
| EP-0619704-A1 | METHOD AND COMPOSITION FOR TREATING TUMORS HAVING HIGH TYROSINASE ACTIVITY | Rubin, David (US) | 1994-10-19 | — | — | EP | disclosed |
| US-5340803-A | Method and compositions for treating tumors having high tyrosinase activity | CO ENZYME TECHNOLOGY LTD. (US) | 1994-08-23 | — | — | US | disclosed |
| US-5240914-A | Method and compositions for inhibiting tumor cell metabolism | Schwimmer, Adolph (US) | 1993-08-31 | — | — | US | disclosed |
| WO-1993008688-A1 | METHOD AND COMPOSITION FOR TREATING TUMORS HAVING HIGH TYROSINASE ACTIVITY | SCHWIMMER, ADOLPH (US) | 1993-05-13 | — | — | WO | disclosed |
| US-4584368-A | β-Glucuronidase activity and/or pH-dependent pharmaceuticals and thier methods of production | Schwimmer, Adolf W. (IL) | 1986-04-22 | — | — | US | disclosed |
| US-4337760-A | Method for the treatment of tumors with β-glucuronidase activity dependent pharmaceuticals | Schwimmer, Adolf (IL) | 1982-07-06 | — | — | US | disclosed |
| US-4327074-A | Method for diagnosis and selective treatment of infections of bacteria having β-glucuronidase activity | Schwimmer, Adolf W. | 1982-04-27 | — | — | US | disclosed |
| WO-1980000791-A1 | B-GLUCURONIDASE ACTIVITY AND/OR PH-DEPENDENT PHARMACEUTICALS AND THEIR METHODS OF PRODUCTION AND USE FOR SELECTIVE TREATMENT OF DISEASES | SCHWIMMER A (US) | 1980-05-01 | — | — | WO | disclosed |