Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 4/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15375667 | 1.00 | ACACB (0.39) | ACACBKMT2ATLR2CASP3TAS1R3 | |
| SCHEMBL3018189 | 0.92 | ACACB (0.40) | ACACBKMT2ATLR2CASP3PIN1 | |
| SCHEMBL3018006 | 0.88 | KMT2A (0.40) | ACACBKMT2ACASP3PIN1 | |
| SCHEMBL3012552 | 0.88 | CASP3 (0.43) | KMT2ACASP3PIN1 | |
| SCHEMBL3802721 | 0.88 | KMT2A (0.44) | ACACBKMT2ATLR2CASP3PIN1 | |
| SCHEMBL3015812 | 0.88 | KMT2A (0.44) | ACACBKMT2ATLR2CASP3PIN1 | |
| SCHEMBL3018948 | 0.86 | KMT2A (0.43) | KMT2ACASP3PIN1 | |
| SCHEMBL3808020 | 0.86 | KMT2A (0.43) | KMT2ACASP3PIN1 | |
| SCHEMBL15375665 | 0.85 | KMT2A (0.38) | ACACBKMT2ATLR2CASP3PIN1 | |
| SCHEMBL13984775 | 0.84 | CASP3 (0.41) | KMT2ACASP3PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2662353-A2 | Antibacterial agents | Achaogen, Inc. (US) | 2013-11-13 | — | — | EP | disclosed |