Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11307896 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2HTTLMNAFKBP5CRBN | |
| SCHEMBL8961691 | 0.82 | — | — | |
| SCHEMBL11166997 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2HTTLMNAFKBP5CRBN | |
| SCHEMBL518177 | 0.79 | — | — | |
| SCHEMBL18183400 | 0.76 | SMN1; SMN2 (0.48) | SMN1; SMN2HTTLMNAFKBP5CRBN | |
| Caprolactam SCHEMBL16112032 | 0.73 | CRBN (0.70) | SMN1; SMN2FKBP5CRBNCCR2KDM4E | |
| SCHEMBL90036 | 0.73 | — | — | |
| Piperidine SCHEMBL29043025 | 0.71 | ALDH1A1 (0.56) | SMN1; SMN2LMNAFFAR3LCKFYN | |
| Piperidine SCHEMBL10332243 | 0.71 | ALDH1A1 (0.56) | SMN1; SMN2LMNAFFAR3LCKFYN | |
| Piperidine SCHEMBL192668 | 0.71 | ALDH1A1 (0.56) | SMN1; SMN2LMNAFFAR3LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2664585-B1 | PLANT-DERIVED FLOCCULANT, FLOCCULANT MIXTURE, METHOD OF FLOCCULATION, AND METHOD FOR PREPARING PLANT-DERIVED FLOCCULANT | SONY CORP (JP) | 2018-09-12 | — | — | EP | disclosed |
| US-9611157-B2 | Plant-derived flocculant, flocculant mixture, method of flocculation, and method for preparing plant-derived flocculant | SONY CORPORATION (JP) | 2017-04-04 | — | — | US | disclosed |
| EP-2664585-A1 | PLANT-DERIVED FLOCCULANT, FLOCCULANT MIXTURE, METHOD OF FLOCCULATION, AND METHOD FOR PREPARING PLANT-DERIVED FLOCCULANT | Sony Corporation (JP) | 2013-11-20 | — | — | EP | disclosed |
| US-20130299433-A1 | PLANT-DERIVED FLOCCULANT, FLOCCULANT MIXTURE, METHOD OF FLOCCULATION, AND METHOD FOR PREPARING PLANT-DERIVED FLOCCULANT | SONY CORPORATION (JP) | 2013-11-14 | — | — | US | disclosed |