Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.51 |
| ▸ | YAP1 | P46937 | 1/20 | 0.51 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.51 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | AHR | P35869 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1006030 | 0.79 | MAPT (0.67) | ALDH1A1TEAD1YAP1TEAD4TEAD2 | |
| SCHEMBL650804 | 0.79 | ALDH1A1 (0.54) | ALDH1A1TEAD1YAP1TEAD4TEAD2 | |
| SCHEMBL15155615 | 0.79 | ALDH1A1 (0.54) | ALDH1A1TEAD1YAP1TEAD4TEAD2 | |
| SCHEMBL29782538 | 0.78 | MAPT (0.55) | ALDH1A1TEAD1YAP1TEAD4TEAD2 | |
| SCHEMBL29994325 | 0.78 | TEAD1 (0.55) | ALDH1A1TEAD1YAP1TEAD4TEAD2 | |
| SCHEMBL6382634 | 0.78 | ALDH1A1 (0.53) | ALDH1A1TEAD1YAP1TEAD4TEAD2 | |
| SCHEMBL353910 | 0.78 | KCNH2 (0.58) | ALDH1A1TEAD1YAP1TEAD4TEAD2 | |
| SCHEMBL30224972 | 0.75 | CYP3A4 (0.54) | ALDH1A1TEAD1YAP1TEAD4TEAD2 | |
| SCHEMBL9782978 | 0.74 | MAPT (0.51) | ALDH1A1TEAD1YAP1TEAD4TEAD2 | |
| SCHEMBL7574372 | 0.74 | CAPN1 (0.54) | ALDH1A1TEAD1YAP1TEAD4TEAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2847184-A1 | 5-HALOGENOPYRAZOLE BENZOFURANYL CARBOXAMIDES | Bayer CropScience AG (DE) | 2015-03-18 | — | — | EP | disclosed |
| WO-2013167551-A1 | 5-HALOGENOPYRAZOLE BENZOFURANYL CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2013-11-14 | — | — | WO | disclosed |