SCHEMBL30224972

SCHEMBL30224972

NC(=O)c1oc2ccccc2c(=O)c1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.54
KDM4E B2RXH2 6/20 0.54
MEN1 O00255 6/20 0.54
KMT2A Q03164 6/20 0.54
MAPK1 P28482 4/20 0.54
ALOX15 P16050 3/20 0.54
TP53 P04637 3/20 0.54
LMNA P02545 2/20 0.54
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
ABCB1 P08183 1/20 0.54
CALM1 P0DP23 1/20 0.54
AR P10275 1/20 0.54
PKM P14618 1/20 0.54
CYP1B1 Q16678 1/20 0.54
CA9 Q16790 1/20 0.54
ALDH1A1 P00352 6/20 0.52
HSD17B10 Q99714 5/20 0.52
MAOA P21397 5/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL650804 0.87 ALDH1A1 (0.54) CYP3A4KDM4EMEN1KMT2AMAPK1
SCHEMBL752884 0.84 KDM4E (0.65) CYP3A4KDM4EMEN1KMT2AMAPK1
SCHEMBL9782978 0.81 MAPT (0.51) CYP3A4KDM4EKMT2ATP53PKM
SCHEMBL7574372 0.81 CAPN1 (0.54) CYP3A4KDM4EMEN1KMT2ATP53
SCHEMBL11492748 0.80 MAPT (0.62) CYP3A4KDM4EMEN1KMT2AMAPK1
SCHEMBL28291736 0.79 CA1 (0.62) CYP3A4KDM4EMEN1KMT2AMAPK1
SCHEMBL8802227 0.77 KDM4E (0.59) CYP3A4KDM4EMEN1KMT2AMAPK1
SCHEMBL28301960 0.77 CYP3A4 (0.59) CYP3A4KDM4EMEN1KMT2AMAPK1
SCHEMBL1006030 0.77 MAPT (0.67) KDM4EMEN1KMT2ATP53ALDH1A1
SCHEMBL15155615 0.77 ALDH1A1 (0.54) KDM4EMEN1KMT2ATP53PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109641864-B Anti-infective agents 邓迪大学 2023-04-04 CN disclosed